Paul V Sabatini
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Explore the profile of Paul V Sabatini including associated specialties, affiliations and a list of published articles.
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15
Citations
212
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Recent Articles
1.
Ludwig M, Coester B, Gordian D, Hassan S, Tomlinson A, Toure M, et al.
bioRxiv
. 2025 Jan;
PMID: 39868309
Amylin analogs, including potential anti-obesity therapies like cagrilintide, act on neurons in the brainstem dorsal vagal complex (DVC) that express calcitonin receptors (CALCR). These receptors, often combined with receptor activity-modifying...
2.
Markam P, Bourguignon C, Zhu L, Ward B, Darvas M, Sabatini P, et al.
Sci Adv
. 2025 Jan;
11(1):eado9965.
PMID: 39742489
Infradian mood and sleep-wake rhythms with periods of 48 hours and beyond have been observed in patients with bipolar disorder (BD), which even persist in the absence of exogenous timing...
3.
Hes C, Gui L, Bay A, Alvarez F, Katz P, Paul T, et al.
Mol Metab
. 2024 Nov;
91():102070.
PMID: 39608751
Objective: Growth differentiation factor 15 (GDF15) acts on the receptor dimer of GDNF family receptor alpha-like (GFRAL) and Rearranged during transfection (RET). While Gfral-expressing cells are known to be present...
4.
Markam P, Bourguignon C, Zhu L, Darvas M, Sabatini P, Kokoeva M, et al.
bioRxiv
. 2023 Nov;
PMID: 38014299
Infradian mood and sleep-wake rhythms with periods of 48 hr and beyond have been observed in bipolar disorder (BD) subjects that even persist in time isolation, indicating an endogenous origin....
5.
Patel A, Frikke-Schmidt H, Sabatini P, Rupp A, Sandoval D, Myers Jr M, et al.
Am J Physiol Regul Integr Comp Physiol
. 2023 Mar;
PMID: 36912475
Deoxynivalenol (DON), a type B trichothecene mycotoxin contaminating grains, promotes nausea, emesis and anorexia. With DON exposure, circulating levels of intestinally derived satiation hormones, including glucagon-like peptide 1 (GLP-1) are...
6.
Patel A, Frikke-Schmidt H, Bezy O, Sabatini P, Rittig N, Jessen N, et al.
Am J Physiol Gastrointest Liver Physiol
. 2021 Dec;
322(2):G247-G255.
PMID: 34935522
Growth differentiation factor 15 (GDF15), a TGFβ superfamily cytokine, acts through its receptor, cell line-derived neurotrophic factorfamily receptor α-like (GFRAL), to suppress food intake and promote nausea. GDF15 is broadly...
7.
Affinati A, Sabatini P, True C, Tomlinson A, Kirigiti M, Lindsley S, et al.
Elife
. 2021 May;
10.
PMID: 34018926
The ventromedial hypothalamic nucleus (VMH) controls diverse behaviors and physiologic functions, suggesting the existence of multiple VMH neural subtypes with distinct functions. Combing translating ribosome affinity purification with RNA-sequencing (TRAP-seq)...
8.
Sabatini P, Wang J, Rupp A, Affinati A, Flak J, Li C, et al.
Elife
. 2021 Mar;
10.
PMID: 33704065
While Cre-dependent viral systems permit the manipulation of many neuron types, some cell populations cannot be targeted by a single DNA recombinase. Although the combined use of Flp and Cre...
9.
Sabatini P, Frikke-Schmidt H, Arthurs J, Gordian D, Patel A, Rupp A, et al.
Proc Natl Acad Sci U S A
. 2021 Feb;
118(8).
PMID: 33593916
The TGFβ cytokine family member, GDF-15, reduces food intake and body weight and represents a potential treatment for obesity. Because the brainstem-restricted expression pattern of its receptor, GDNF Family Receptor...
10.
Flak J, Goforth P, DellOrco J, Sabatini P, Li C, Bozadjieva N, et al.
J Clin Invest
. 2020 Mar;
130(6):2943-2952.
PMID: 32134398
To identify neurons that specifically increase blood glucose from among the diversely functioning cell types in the ventromedial hypothalamic nucleus (VMN), we studied the cholecystokinin receptor B-expressing (CCKBR-expressing) VMN targets...