Paul Rosch
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Explore the profile of Paul Rosch including associated specialties, affiliations and a list of published articles.
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81
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1373
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Recent Articles
1.
Adolph R, Beck E, Schweimer K, di Fonzo A, Weyand M, Rosch P, et al.
Life (Basel)
. 2023 Apr;
13(4).
PMID: 37109478
Sirtuins are NAD-dependent protein lysine deacylases implicated in metabolic regulation and aging-related dysfunctions. The nuclear isoform Sirt1 deacetylates histones and transcription factors and contributes, e.g., to brain and immune cell...
2.
Beteinakis S, Papachristodoulou A, Kolb P, Rosch P, Schwarzinger S, Mikros E, et al.
Molecules
. 2023 Feb;
28(4).
PMID: 36838725
Extra virgin olive oil (EVOO) possesses a high-value rank in the food industry, thus making it a common target for adulteration. Hence, several methods have been essentially made available over...
3.
Jacob T, von Loetzen C, Reuter A, Lacher U, Schiller D, Schobert R, et al.
Sci Rep
. 2019 Jun;
9(1):8714.
PMID: 31213622
Hazelnut is one of the most frequent causes of food allergy. The major hazel allergen in Northern Europe is Cor a 1, which is homologous to the major birch pollen...
4.
Zuber P, Schweimer K, Rosch P, Artsimovitch I, Knauer S
Nat Commun
. 2019 Feb;
10(1):702.
PMID: 30742024
RfaH, member of the NusG/Spt5 family, activates virulence genes in Gram-negative pathogens. RfaH exists in two states, with its C-terminal domain (CTD) folded either as α-helical hairpin or β-barrel. In...
5.
von Loetzen C, Reuter A, Spiric J, Schulenborg T, Bellinghausen I, Volker E, et al.
Clin Exp Allergy
. 2019 Feb;
49(5):712-723.
PMID: 30706562
Background: To date, only limited information on structure, expression levels and IgE binding of Bet v 1 variants, which are simultaneously expressed in birch pollen, is available. Objective: To analyse...
6.
Zuber P, Hahn L, Reinl A, Schweimer K, Knauer S, Gottesman M, et al.
Sci Rep
. 2018 Aug;
8(1):11660.
PMID: 30076330
The human transcription elongation factor DSIF is highly conserved throughout all kingdoms of life and plays multiple roles during transcription. DSIF is a heterodimer, consisting of Spt4 and Spt5 that...
7.
Rib-Schmidt C, Riedl P, Meisinger V, Schwaben L, Schulenborg T, Reuter A, et al.
Mol Nutr Food Res
. 2018 May;
62(15):e1700886.
PMID: 29800504
Scope: The major celery allergen Api g 1 is a member of the pathogenesis-related 10 class protein family. This study aims to investigate the impact of heat and pH on...
8.
Zuber P, Artsimovitch I, Nandymazumdar M, Liu Z, Nedialkov Y, Schweimer K, et al.
Elife
. 2018 May;
7.
PMID: 29741479
RfaH, a transcription regulator of the universally conserved NusG/Spt5 family, utilizes a unique mode of recruitment to elongating RNA polymerase to activate virulence genes. RfaH function depends critically on an...
9.
Drogemuller J, Schneider C, Schweimer K, Strauss M, Wohrl B, Rosch P, et al.
Nucleic Acids Res
. 2016 Dec;
45(1):446-460.
PMID: 27899597
NusG, the only universally conserved transcription factor, comprises an N- and a C-terminal domain (NTD, CTD) that are flexibly connected and move independently in Escherichia coli and other organisms. In...
10.
Seufert F, Kuhn M, Hein M, Weiwad M, Vivoli M, Norville I, et al.
Bioorg Med Chem
. 2016 Sep;
24(21):5134-5147.
PMID: 27591009
The bacteria Burkholderia pseudomallei and Legionella pneumophila cause severe diseases like melioidosis and Legionnaire's disease with high mortality rates despite antibiotic treatment. Due to increasing antibiotic resistances against these and...