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Paul R Buckley

Explore the profile of Paul R Buckley including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Lee C, Huh J, Buckley P, Jang M, Pinho M, Fernandes R, et al.
Genome Med . 2023 Sep; 15(1):70. PMID: 37705109
Background: T-cells play a crucial role in the adaptive immune system by triggering responses against cancer cells and pathogens, while maintaining tolerance against self-antigens, which has sparked interest in the...
2.
Buckley P, Lee C, Antanaviciute A, Simmons A, Koohy H
Immunother Adv . 2023 Apr; 3(1):ltad005. PMID: 37082106
T cell recognition of SARS-CoV-2 antigens after vaccination and/or natural infection has played a central role in resolving SARS-CoV-2 infections and generating adaptive immune memory. However, the clinical impact of...
3.
Buckley P, Lee C, Ma R, Woodhouse I, Woo J, Tsvetkov V, et al.
Brief Bioinform . 2022 Apr; 23(3). PMID: 35471658
T cell recognition of a cognate peptide-major histocompatibility complex (pMHC) presented on the surface of infected or malignant cells is of the utmost importance for mediating robust and long-term immune...
4.
Buckley P, Lee C, Pinho M, Ottakandathil Babu R, Woo J, Antanaviciute A, et al.
Immunology . 2022 Feb; 166(1):78-103. PMID: 35143694
The conditions and extent of cross-protective immunity between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and common-cold human coronaviruses (HCoVs) remain open despite several reports of pre-existing T cell immunity...
5.
Lee C, Pinho M, Buckley P, Woodhouse I, Ogg G, Simmons A, et al.
Front Immunol . 2020 Nov; 11:579480. PMID: 33250893
While individuals infected with coronavirus disease 2019 (COVID-19) manifested a broad range in susceptibility and severity to the disease, the pre-existing immune memory to related pathogens cross-reactive against SARS-CoV-2 can...
6.
Buckley P, Alden K, Coccia M, Chalon A, Collignon C, Temmerman S, et al.
Front Immunol . 2019 Oct; 10:2150. PMID: 31572370
Novel adjuvant technologies have a key role in the development of next-generation vaccines, due to their capacity to modulate the duration, strength and quality of the immune response. The AS01...