Paul Kwong Hang Tam
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Explore the profile of Paul Kwong Hang Tam including associated specialties, affiliations and a list of published articles.
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71
Citations
925
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Recent Articles
1.
Wang W, Lian H, Liang Y, Ye Y, Tam P, Chen Y
Cells
. 2024 Dec;
13(23).
PMID: 39682745
The aim of this review is to explore the potential of new regenerative medicine approaches in the treatment of cholestatic liver fibrosis. Cholestatic liver diseases, such as primary biliary cholangitis...
2.
Xie H, Zhu Z, Tang J, Zhu W, Zhu M, Yi Wai A, et al.
Lab Invest
. 2024 Nov;
105(2):102199.
PMID: 39579985
The canonical Hippo-YAP1 signaling pathway is crucial for liver development and regeneration, but its role in repair and regeneration of intrahepatic bile duct in biliary atresia (BA) remains largely unknown....
3.
Wang W, Tam P, Chen Y
World J Gastroenterol
. 2024 Nov;
30(41):4490-4495.
PMID: 39534418
In this article, we comment on the article by Huang . The urgent development of new therapeutic strategies targeting macrophage polarization is critical in the fight against liver cancer. Tumor-associated...
4.
Yi Wai A, Lui V, Tang C, Wang B, Tam P, Wong K, et al.
J Pediatr Surg
. 2024 Sep;
60(2):161686.
PMID: 39271308
Background: Kasai portoenterostomy (KPE) remains the primary intervention for biliary atresia (BA), but its outcomes are highly variable. Reliable prognostic biomarkers remain elusive, complicating the management and prediction of postoperative...
5.
Liu F, Lui V, Wu Z, Blakeley P, Tang C, Tam P, et al.
Pediatr Surg Int
. 2024 Aug;
40(1):214.
PMID: 39102048
Purpose: We performed animal and organoid study to evaluate the anti-fibrotic effect of steroid on biliary atresia (BA) and the underlying patho-mechanism. Methods: BA animal models were created by inoculation...
6.
Ye Y, Tong H, Chong W, Li Z, Tam P, Baptista-Hon D, et al.
Sci Rep
. 2024 Feb;
14(1):4026.
PMID: 38369574
Antibiotics are indispensable to infection management. However, use of antibiotics can cause gut microbiota dysbiosis, which has been linked to cognitive impairment by disrupting communication between the gut microbiota and...
7.
Ye Y, Lui V, Ottakandathil Babu R, Wu Z, Wu W, Chung P, et al.
PLoS One
. 2023 Mar;
18(3):e0283737.
PMID: 36996081
Background: Choledochal cysts (CC) are congenital bile duct anomalies with 6-30% risk for developing bile duct cancer. However, the molecular mechanisms underlying cancer risk of CC are unknown. We sought...
8.
Li J, Chu J, Lui V, Chen S, Chen Y, Tam P
Bioengineering (Basel)
. 2022 Dec;
9(12).
PMID: 36551002
Organoids as three-dimension (3D) cellular organizations partially mimic the physiological functions and micro-architecture of native tissues and organs, holding great potential for clinical applications. Advances in the identification of essential...
9.
Hei Ha J, Lui V, Tam P
Semin Pediatr Surg
. 2022 Nov;
31(6):151227.
PMID: 36417785
Bowel has its own elegant nervous system - the enteric nervous system (ENS) which is a complex network of neurons and glial clones. Derived from neural crest cells (NCCs), this...
10.
Lyu H, Ye Y, Lui V, Wu W, Chung P, Wong K, et al.
Front Surg
. 2022 Sep;
9:931637.
PMID: 36132201
Background: Biliary atresia (BA) is an infantile fibro-obstructive cholestatic disease with poor prognosis. An early diagnosis and timely Kasai portoenterostomy (KPE) improve clinical outcomes. Aggregation of amyloid-beta (Aβ) around hepatic...