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Mai Har Sham

Explore the profile of Mai Har Sham including associated specialties, affiliations and a list of published articles. Areas
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Articles 43
Citations 713
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Recent Articles
1.
Wei T, Lin R, Lu Y, Jin D, Zhang J, Sham M
Int J Biol Sci . 2025 Feb; 21(3):1081-1096. PMID: 39897043
Glioma is the most prevalent and deadly type of intracranial tumor. Understanding the molecular drivers and their underlying mechanisms in glioma development is urgently needed. EYA1 is a unique protein...
2.
Fritzsch B, Weng X, Yamoah E, Qin T, Hui C, Lebron-Mora L, et al.
J Comp Neurol . 2024 Dec; 532(12):e70008. PMID: 39655644
A gene cadre orchestrates the normal development of sensory and non-sensory cells in the inner ear, segregating the cochlea with a distinct tonotopic sound frequency map, similar brain projection, and...
3.
Liu Y, Qin T, Weng X, Leung B, So K, Wang B, et al.
bioRxiv . 2024 Nov; PMID: 39484413
The mammalian inner ear houses the vestibular and cochlear sensory organs dedicated to sensing balance and sound, respectively. These distinct sensory organs arise from a common prosensory region, but the...
4.
Qin T, So K, Hui C, Sham M
Cell Rep . 2024 Apr; 43(4):114083. PMID: 38602877
A common cause of deafness in humans is dysregulation of the endocochlear potential generated by the stria vascularis (SV). Thus, proper formation of the SV is critical for hearing. Using...
5.
Szeto I, Chu D, Chen P, Chu K, Au T, Leung K, et al.
Proc Natl Acad Sci U S A . 2022 Nov; 119(46):e2122121119. PMID: 36343245
The in vivo mechanisms underlying dominant syndromes caused by mutations in SRY-Box Transcription Factor 9 () and () transcription factors, when they either are expressed alone or are coexpressed, are...
6.
Qin T, Ho C, Wang B, Hui C, Sham M
Proc Natl Acad Sci U S A . 2022 Oct; 119(43):e2206571119. PMID: 36252002
Development of mammalian auditory epithelium, the organ of Corti, requires precise control of both cell cycle withdrawal and differentiation. Sensory progenitors (prosensory cells) in the cochlear apex exit the cell...
7.
So K, Huang Y, Zhang S, Qiao Y, He L, Li Y, et al.
Aging Cell . 2022 Jul; 21(8):e13673. PMID: 35851988
Muscle satellite cells (SCs) are responsible for muscle homeostasis and regeneration and lncRNAs play important roles in regulating SC activities. Here, in this study, we identify PAM (Pax7 Associated Muscle...
8.
Huang T, Hou Y, Wang X, Wang L, Yi C, Wang C, et al.
Gastroenterology . 2021 Aug; 162(1):179-192.e11. PMID: 34425092
Background And Aims: The enteric nervous system, which regulates many gastrointestinal functions, is derived from neural crest cells (NCCs). Defective NCC migration during embryonic development may lead to enteric neuropathies...
9.
Zhang H, Xie J, So K, Tong K, Sae-Pang J, Wang L, et al.
Front Physiol . 2021 Jan; 11:612230. PMID: 33505317
Craniofacial morphogenesis depends on proper migration of neural crest cells and their interactions with placodes and other cell types. genes provide positional information and are important in patterning the neural...
10.
Moher D, Bouter L, Kleinert S, Glasziou P, Sham M, Barbour V, et al.
PLoS Biol . 2020 Jul; 18(7):e3000737. PMID: 32673304
For knowledge to benefit research and society, it must be trustworthy. Trustworthy research is robust, rigorous, and transparent at all stages of design, execution, and reporting. Assessment of researchers still...