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Paul J Simmons

Explore the profile of Paul J Simmons including associated specialties, affiliations and a list of published articles. Areas
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Articles 59
Citations 4246
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Recent Articles
1.
Watt S, Buhring H, Simmons P, Zannettino A
NPJ Regen Med . 2021 Jun; 6(1):33. PMID: 34103536
Accurately defining hierarchical relationships between human stem cells and their progeny, and using this knowledge for new cellular therapies, will undoubtedly lead to further successful treatments for life threatening and...
2.
Mokhtari S, Colletti E, Yin W, Sanada C, Lamar Z, Simmons P, et al.
Leukemia . 2018 Jun; 32(7):1670. PMID: 29891936
At the time of publication the funding information was omitted from the article - this has now been corrected in both the HTML and the PDF.
3.
Mokhtari S, Colletti E, Yin W, Sanada C, Lamar Z, Simmons P, et al.
Leukemia . 2018 Feb; 32(7):1575-1586. PMID: 29467489
The presence, within the human bone marrow, of cells with both endothelial and hemogenic potential has been controversial. Herein, we identify, within the human fetal bone marrow, prior to establishment...
4.
Brouard N, Jost C, Matthias N, Albrecht C, Egard S, Gandhi P, et al.
Blood Adv . 2018 Jan; 1(21):1854-1866. PMID: 29296832
The fetal liver is the site of a major expansion of the hematopoietic stem cell (HSC) pool and is also a privileged organ to study megakaryocyte progenitor differentiation. We identified...
5.
Robinson S, Thomas M, Simmons P, Lu J, Yang H, Javni J, et al.
Cytotherapy . 2016 Dec; 19(2):285-292. PMID: 27919572
Background Aims: Despite ethnic diversity and ready availability of cryopreserved, human leukocyte antigen-typed cord blood (CB), delayed engraftment remains a significant hurdle to successful CB transplantation. Suboptimal homing of CB...
6.
Blashki D, Murphy M, Ferrari M, Simmons P, Tasciotti E
J Tissue Eng . 2016 Sep; 7:2041731416661196. PMID: 27579159
In this study, we show that matrix dense cortical bone is the more potent compartment of bone than bone marrow as a stromal source for mesenchymal stem cells as isolated...
7.
Simmons P, Robinson S, Munsell M, Thomas M, Javni J, Brouard N, et al.
Stem Cells Dev . 2015 Feb; 24(9):1066-72. PMID: 25674667
CD34(+) cell dose provides a measure of hematopoietic tissue that predicts the rate of engraftment upon transplant. It is positively correlated with multiple measures of hematopoietic recovery, including platelet engraftment....
8.
Murphy M, Blashki D, Buchanan R, Fan D, De Rosa E, Shah R, et al.
J Funct Biomater . 2014 Jun; 2(2):39-66. PMID: 24956163
A novel bioactive sponge was created with a composite of type I collagen sponges or porous poly(e-caprolactone) (PCL) scaffolds, platelet-rich plasma (PRP), BMP2-loaded nanoporous silicon enclosure (NSE) microparticles, mineralizing peptide...
9.
Martin I, Simmons P, Williams D
Sci Transl Med . 2014 Apr; 6(232):232fs16. PMID: 24739757
Along with scientific and regulatory issues, the translation of cell and tissue therapies in the routine clinical practice needs to address standardization and cost-effectiveness through the definition of suitable manufacturing...
10.
Robinson S, Thomas M, Simmons P, Lu J, Yang H, Parmar S, et al.
Cytotherapy . 2013 Oct; 16(1):84-9. PMID: 24094497
Background Aims: Advantages associated with the use of cord blood (CB) transplantation include the availability of cryopreserved units, ethnic diversity and lower incidence of graft-versus-host disease compared with bone marrow...