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Patrick A Zweidler-McKay

Explore the profile of Patrick A Zweidler-McKay including associated specialties, affiliations and a list of published articles. Areas
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Articles 59
Citations 2327
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Recent Articles
1.
Watts B, Smith C, Evans K, Gifford A, Mohamed S, Erickson S, et al.
Hemasphere . 2025 Jan; 9(1):e70063. PMID: 39830370
Antibody-drug conjugates (ADCs) combining monoclonal antibodies with cytotoxic payloads are a rapidly emerging class of immune-based therapeutics with the potential to improve the treatment of cancer, including children with relapse/refractory...
2.
Hayashi R, Hermiston M, Wood B, Teachey D, Devidas M, Chen Z, et al.
Blood . 2024 Mar; 143(20):2053-2058. PMID: 38457359
Defining prognostic variables in T-lymphoblastic lymphoma (T-LL) remains a challenge. AALL1231 was a Children's Oncology Group phase 3 clinical trial for newly diagnosed patients with T acute lymphoblastic leukemia or...
3.
Daver N, Montesinos P, DeAngelo D, Wang E, Papadantonakis N, Todisco E, et al.
Lancet Oncol . 2024 Feb; 25(3):388-399. PMID: 38423051
Background: Pivekimab sunirine (IMGN632) is a first-in-class antibody-drug conjugate comprising a high-affinity CD123 antibody, cleavable linker, and novel indolinobenzodiazepine pseudodimer payload. CD123 is overexpressed in several haematological malignancies, including acute...
4.
Fuentes-Mattei E, Bayraktar R, Manshouri T, Silva A, Ivan C, Gulei D, et al.
JCI Insight . 2024 Feb; 9(3). PMID: 38329131
No abstract available.
5.
Wood B, Devidas M, Summers R, Chen Z, Asselin B, Rabin K, et al.
Blood . 2023 Aug; 142(24):2069-2078. PMID: 37556734
The early thymic precursor (ETP) immunophenotype was previously reported to confer poor outcome in T-cell acute lymphoblastic leukemia (T-ALL). Between 2009 and 2014, 1256 newly diagnosed children and young adults...
6.
Gossai N, Devidas M, Chen Z, Wood B, Zweidler-McKay P, Rabin K, et al.
Blood . 2023 Jan; 141(15):1802-1811. PMID: 36603187
To determine the prognostic significance of central nervous system (CNS) leukemic involvement in newly diagnosed T-cell acute lymphoblastic leukemia (T-ALL), outcomes on consecutive, phase 3 Children's Oncology Group clinical trials...
7.
Brady S, Roberts K, Gu Z, Shi L, Pounds S, Pei D, et al.
Nat Genet . 2022 Sep; 54(9):1376-1389. PMID: 36050548
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Here, using whole-genome, exome and transcriptome sequencing of 2,754 childhood patients with ALL, we find that, despite a generally low...
8.
Kannan S, Irwin M, Herbrich S, Cheng T, Patterson L, Aitken M, et al.
Antioxidants (Basel) . 2022 Apr; 11(4). PMID: 35453402
Acute myeloid leukemia (AML) is a molecularly heterogenous hematological malignancy, with one of the most common mutations being internal tandem duplication (ITD) of the juxtamembrane domain of the fms-like tyrosine...
9.
Dunsmore K, Winter S, Devidas M, Wood B, Esiashvili N, Chen Z, et al.
J Clin Oncol . 2020 Aug; 38(28):3282-3293. PMID: 32813610
Purpose: Nelarabine is effective in inducing remission in patients with relapsed and refractory T-cell acute lymphoblastic leukemia (T-ALL) but has not been fully evaluated in those with newly diagnosed disease....
10.
Salzer W, Burke M, Devidas M, Dai Y, Hardy K, Kairalla J, et al.
J Clin Oncol . 2020 Jun; 38(23):2628-2638. PMID: 32496902
Purpose: The high-risk stratum of Children's Oncology Group Study AALL1131 was designed to test the hypothesis that postinduction CNS prophylaxis with intrathecal triple therapy (ITT) including methotrexate, hydrocortisone, and cytarabine...