Paul J Kostyniak
Overview
Explore the profile of Paul J Kostyniak including associated specialties, affiliations and a list of published articles.
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31
Citations
571
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Recent Articles
1.
VanEtten S, Bonner M, Ren X, Birnbaum L, Kostyniak P, Wang J, et al.
Toxicology
. 2021 Mar;
454:152744.
PMID: 33677009
Mitochondria are intracellular organelles responsible for biological oxidation and energy production. These organelles are susceptible to damage from oxidative stress and compensate for damage by increasing the number of copies...
2.
VanEtten S, Bonner M, Ren X, Birnbaum L, Kostyniak P, Wang J, et al.
Toxicol Appl Pharmacol
. 2020 Oct;
408:115264.
PMID: 33022284
Telomere length (TL) can be affected by various factors, including age and oxidative stress. Changes in TL have been associated with chronic disease, including a higher risk for several types...
3.
Ellsworth R, Kostyniak P, Chi L, Shriver C, Costantino N, Ellsworth D
Environ Toxicol
. 2018 Jun;
PMID: 29923341
Agricultural pesticides are abundant environmental contaminants worldwide, prompting interest in studying their possible detrimental health effects. We examined organochlorine residues by quadrant (n = 245) in breast adipose tissues from...
4.
Ellsworth R, Mamula K, Costantino N, Deyarmin B, Kostyniak P, Chi L, et al.
Environ Res
. 2015 Mar;
138:291-7.
PMID: 25749124
Many environmental chemicals accumulate in human tissues and may contribute to cancer risk. Polychlorinated biphenyls (PCBs) are associated with adverse health effects, but relationships between PCB exposure and breast cancer...
5.
Willsky G, Halvorsen K, Godzala 3rd M, Chi L, Most M, Kaszynski P, et al.
Metallomics
. 2013 Aug;
5(11):1491-502.
PMID: 23982218
Vanadium, abbreviated V, is an early transition metal that readily forms coordination complexes with a variety of biological products such as proteins, metabolites, membranes and other structures. The formation of...
6.
Poon E, Monaikul S, Kostyniak P, Chi L, Schantz S, Sable H
Neurotoxicol Teratol
. 2013 Apr;
38:6-12.
PMID: 23623962
PCBs have long been known to affect dopamine (DA) function in the brain. The current study used an amphetamine behavioral sensitization paradigm in rats developmentally exposed to PCBs. Long-Evans rats...
7.
Willsky G, Chi L, Godzala 3rd M, Kostyniak P, Smee J, Trujillo A, et al.
Coord Chem Rev
. 2012 Oct;
255(19-20):2258-2269.
PMID: 23049138
The effects of oral treatment of rats with streptozotocin-induced diabetes with a range of vanadium dipicolinate complexes (Vdipic) and derivatives are reviewed. Structure-reactivity relationships are explored aiming to correlate properties...
8.
Mitchell M, Woods R, Chi L, Schmidt R, Pessah I, Kostyniak P, et al.
Environ Mol Mutagen
. 2012 Aug;
53(8):589-98.
PMID: 22930557
Persistent organic pollutants (POPs), including polychlorinated biphenyls (PCBs) and polybrominated diphenylethers (PBDEs) that bioaccumulate in lipid-rich tissues are of concern as developmental neurotoxicants. Epigenetic mechanisms such as DNA methylation act...
9.
Lynch C, Jackson L, Kostyniak P, McGuinness B, Buck Louis G
Reprod Toxicol
. 2012 May;
34(3):451-6.
PMID: 22569275
We examined the association between prenatal and postnatal exposure to PCBs and development at age 24 months as measured by the Bayley Scales of Infant Development II. 44 (85%) of...
10.
Woods R, Vallero R, Golub M, Suarez J, Ta T, Yasui D, et al.
Hum Mol Genet
. 2012 Feb;
21(11):2399-411.
PMID: 22343140
The widespread use of persistent organic polybrominated diphenyl ethers (PBDEs) as commercial flame retardants has raised concern about potential long-lived effects on human health. Epigenetic mechanisms, such as DNA methylation,...