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Paul J Adams

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Articles 12
Citations 224
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Recent Articles
1.
Sack A, Samera G, Hissen A, Wester R, Garcia E, Adams P, et al.
Mol Brain . 2024 Nov; 17(1):82. PMID: 39568055
P/Q-type (Ca2.1) calcium channels mediate Ca influx essential for neuronal excitability and synaptic transmission. The CACNA1A gene, encoding the Ca2.1 pore forming subunit, is highly expressed throughout the mammalian central...
2.
Biesheuvel M, Kalbfleisch K, De Buck J, van Engelen E, van Schaik G, Moroni P, et al.
Microbiol Spectr . 2024 Aug; 12(10):e0094624. PMID: 39162555
Importance: Current spp. culture protocols lack empirical derivation concerning carbon dioxide (CO) supplementation and are primarily based on the initial cultivation of . This study indicates that the suitable range...
3.
Wester R, Baillie L, McCarthy G, Keever C, Jeffery L, Adams P
Sci Rep . 2024 Jun; 14(1):12903. PMID: 38839848
Free Fecal Liquid (FFL), also termed Fecal Water Syndrome (FWS), is an ailment in horses characterized by variable solid and liquid (water) phases at defecation. The liquid phase can be...
4.
Moore J, Pepe P, Scheppke K, Lick C, Duval S, Holley J, et al.
Resuscitation . 2022 Aug; 179:9-17. PMID: 35933057
Background: Survival after out-of-hospital cardiac arrest (OHCA) remains poor. A physiologically distinct cardiopulmonary resuscitation (CPR) strategy consisting of (1) active compression-decompression CPR and/or automated CPR, (2) an impedance threshold device,...
5.
Moore J, Duval S, Lick C, Holley J, Scheppke K, Salverda B, et al.
Resuscitation . 2021 Nov; 170:63-69. PMID: 34793874
Objectives: Resuscitation in the Head Up position improves outcomes in animals treated with active compression decompression cardiopulmonary resuscitation and an impedance threshold device (ACD + ITD CPR).We assessed impact of...
6.
Dick I, Limpitikul W, Niu J, Banerjee R, Issa J, Ben-Johny M, et al.
Channels (Austin) . 2015 Jul; 10(1):20-32. PMID: 26176690
David T. Yue was a renowned biophysicist who dedicated his life to the study of Ca(2+) signaling in cells. In the wake of his passing, we are left not only...
7.
Ben-Johny M, Dick I, Sang L, Limpitikul W, Kang P, Niu J, et al.
Curr Mol Pharmacol . 2015 May; 8(2):188-205. PMID: 25966688
Voltage-gated Na and Ca(2+) channels represent two major ion channel families that enable myriad biological functions including the generation of action potentials and the coupling of electrical and chemical signaling...
8.
Lee S, Adams P, Yue D
J Physiol . 2015 Mar; 593(13):2753-78. PMID: 25809476
Key Points: CaV 2.1 channels constitute a dominant Ca(2+) entry pathway into brain neurons, triggering downstream Ca(2+) -dependent processes such as neurotransmitter release. CaV 2.1 is itself modulated by Ca(2+)...
9.
Adams P, Ben-Johny M, Dick I, Inoue T, Yue D
Cell . 2014 Nov; 159(3):608-22. PMID: 25417111
The Ca(2+)-free form of calmodulin (apoCaM) often appears inert, modulating target molecules only upon conversion to its Ca(2+)-bound form. This schema has appeared to govern voltage-gated Ca(2+) channels, where apoCaM...
10.
Bazzazi H, Ben Johny M, Adams P, Soong T, Yue D
Cell Rep . 2013 Oct; 5(2):367-77. PMID: 24120865
CaV1.3 ion channels are dominant Ca(2+) portals into pacemaking neurons, residing at the epicenter of brain rhythmicity and neurodegeneration. Negative Ca(2+) feedback regulation of CaV1.3 channels (CDI) is therefore critical...