Paul H Miller
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Explore the profile of Paul H Miller including associated specialties, affiliations and a list of published articles.
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14
Citations
250
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Recent Articles
1.
Knapp D, Hammond C, Wang F, Aghaeepour N, Miller P, Beer P, et al.
Blood
. 2019 Jan;
133(9):927-939.
PMID: 30622121
Recent advances in single-cell molecular analytical methods and clonal growth assays are enabling more refined models of human hematopoietic lineage restriction processes to be conceptualized. Here, we report the results...
2.
Knapp D, Hammond C, Hui T, van Loenhout M, Wang F, Aghaeepour N, et al.
Nat Cell Biol
. 2018 May;
20(6):710-720.
PMID: 29802403
Elucidation of the identity and diversity of mechanisms that sustain long-term human blood cell production remains an important challenge. Previous studies indicate that, in adult mice, this property is vested...
3.
Miller P, Rabu G, MacAldaz M, Knapp D, Cheung A, Dhillon K, et al.
Exp Hematol
. 2017 Jan;
48:41-49.
PMID: 28087429
Xenograft models are transforming our understanding of the output capabilities of primitive human hematopoietic cells in vivo. However, many variables that affect posttransplantation reconstitution dynamics remain poorly understood. Here, we...
4.
Knapp D, Hammond C, Miller P, Rabu G, Beer P, Ricicova M, et al.
Stem Cell Reports
. 2017 Jan;
8(1):152-162.
PMID: 28076756
The role of growth factors (GFs) in controlling the biology of human hematopoietic stem cells (HSCs) remains limited by a lack of information concerning the individual and combined effects of...
5.
Lorzadeh A, Bilenky M, Hammond C, Knapp D, Li L, Miller P, et al.
Cell Rep
. 2016 Nov;
17(8):2112-2124.
PMID: 27851972
Nucleosome position, density, and post-translational modification are widely accepted components of mechanisms regulating DNA transcription but still incompletely understood. We present a modified native ChIP-seq method combined with an analytical...
6.
Knapp D, Hammond C, Aghaeepour N, Miller P, Pellacani D, Beer P, et al.
Blood
. 2016 Nov;
129(3):307-318.
PMID: 27827829
Several growth factors (GFs) that together promote quiescent human hematopoietic stem cell (HSC) expansion ex vivo have been identified; however, the molecular mechanisms by which these GFs regulate the survival,...
7.
Miller P, Nakamichi N, Knapp D, Rabu G, Schultz K, Jones D, et al.
Biol Blood Marrow Transplant
. 2016 Aug;
22(11):1945-1952.
PMID: 27496214
Plerixafor (P) together with granulocyte colony-stimulating factor (G) is now recognized as an important strategy for mobilizing hematopoietic cells for use in patients given myelosuppressive therapies. However, quantitative comparisons of...
8.
Miller P, Knapp D, Beer P, MacAldaz M, Rabu G, Cheung A, et al.
Exp Hematol
. 2016 Apr;
44(7):635-40.
PMID: 27090409
The critical human cells that produce neutrophils and platelets within 3 weeks in recipients of hematopoietic transplants are thought to produce these mature blood cells with the same kinetics in...
9.
Beer P, Knapp D, Kannan N, Miller P, Babovic S, Bulaeva E, et al.
Stem Cell Reports
. 2014 Nov;
3(5):841-57.
PMID: 25418728
Disrupted IKAROS activity is a recurrent feature of some human leukemias, but effects on normal human hematopoietic cells are largely unknown. Here, we used lentivirally mediated expression of a dominant-negative...
10.
Beer P, Knapp D, Miller P, Kannan N, Sloma I, Heel K, et al.
Blood
. 2014 Nov;
125(3):504-15.
PMID: 25370416
Without effective therapy, chronic-phase chronic myeloid leukemia (CP-CML) evolves into an acute leukemia (blast crisis [BC]) that displays either myeloid or B-lymphoid characteristics. This transition is often preceded by a...