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Paul Ellis

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Articles 60
Citations 4232
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Recent Articles
1.
De Soyza J, Ellis P, Newnham M, Rickard L, Turner A
Chronic Obstr Pulm Dis . 2024 Aug; 11(5):507-514. PMID: 39213377
Introduction: Bronchiectasis occurs in patients with alpha-1 antitrypsin deficiency (AATD), but it is unknown whether an association exists independently of chronic obstructive pulmonary disease (COPD). We assessed whether bronchiectasis was...
2.
Chang C, Emberley E, DSouza A, Zhao W, Cosgrove C, Parrish K, et al.
Blood . 2024 May; 144(7):757-770. PMID: 38701407
Glucocorticoids are key components of the standard-of-care treatment regimens for B-cell malignancy. However, systemic glucocorticoid treatment is associated with several adverse events. ABBV-319 is a CD19-targeting antibody-drug conjugate engineered to...
3.
Ellis P, Parekh G, Duvoix A, Watson L, Sharp A, Mobeen F, et al.
PLoS One . 2024 Feb; 19(2):e0297125. PMID: 38306339
Background: Pulmonary exacerbations in alpha-1 antitrypsin deficiency (AATD) related lung disease are a significant contributor to disease burden, as with usual COPD. Separating the early stages of an exacerbation from...
4.
Ellis P, Bailey E, Choate R, Holm K, Sandhaus R, Turner A, et al.
Int J Chron Obstruct Pulmon Dis . 2024 Jan; 19:149-159. PMID: 38249829
Aim: Alpha-1 antitrypsin deficiency is an autosomal co-dominant condition that predisposes individuals to early-onset emphysema. As with COPD, AATD-COPD is associated with pulmonary exacerbations, which impacts on overall mortality and...
5.
Velikova G, Morden J, Haviland J, Emery C, Barrett-Lee P, Earl H, et al.
Lancet Oncol . 2023 Nov; 24(12):1359-1374. PMID: 37926100
Background: Adjuvant chemotherapy for patients with early breast cancer improves outcomes but its toxicity affects patients' quality of life (QOL). The UK TACT2 trial investigated whether accelerated epirubicin improves time...
6.
Krishnan A, Ellis P, Antoine-Pitterson P, Oakes A, Jones B, Turner A, et al.
Can Respir J . 2023 Oct; 2023:5370197. PMID: 37868785
Introduction: Determinants of long-term mortality following acute hypercapnic respiratory failure have been extensively studied in patients with chronic obstructive pulmonary disease. However, respiratory failure due to obesity has not been...
7.
Burnett B, Zhou S, Brophy S, Davies P, Ellis P, Kennedy J, et al.
Diagnostics (Basel) . 2023 Jan; 13(2). PMID: 36673111
The inclusion of machine-learning-derived models in systematic reviews of risk prediction models for colorectal cancer is rare. Whilst such reviews have highlighted methodological issues and limited performance of the models...
8.
Balu A, Watson A, Linhartova L, Ellis P, Mukherjee R
Respirology . 2021 May; 26(8):727-728. PMID: 34048115
No abstract available.
9.
Santos G, Ellis P, Farrugia D, Turner A
BMJ Case Rep . 2021 Mar; 14(3). PMID: 33674298
We report a 64-year-old caucasian woman diagnosed with membranous nephropathy secondary to alpha-1 antitrypsin deficiency (AATD). AATD is a rare autosomal codominant genetic disorder. Its clinical manifestations are mostly observed...
10.
Fromme M, Schneider C, Pereira V, Hamesch K, Pons M, Reichert M, et al.
Gut . 2021 Feb; 71(2):415-423. PMID: 33632708
Objective: Alpha-1 antitrypsin deficiency (AATD) is a common, potentially lethal inborn disorder caused by mutations in alpha-1 antitrypsin (AAT). Homozygosity for the 'Pi*Z' variant of AAT (Pi*ZZ genotype) causes lung...