Paul E M Phillips
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Explore the profile of Paul E M Phillips including associated specialties, affiliations and a list of published articles.
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77
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6926
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Recent Articles
11.
Steger J, Land B, Lemos J, Chavkin C, Phillips P
Front Behav Neurosci
. 2020 Nov;
14:564054.
PMID: 33132859
Stress is highly pervasive in humans, impacting motivated behaviors with an enormous toll on life quality. Many of the effects of stress are orchestrated by neuropeptides such as corticotropin-releasing factor...
12.
Schattauer S, Land B, Reichard K, Abraham A, Burgeno L, Kuhar J, et al.
Nat Commun
. 2017 Oct;
8(1):743.
PMID: 28963507
Inactivation of opioid receptors limits the therapeutic efficacy of morphine-like analgesics and mediates the long duration of kappa opioid antidepressants by an uncharacterized, arrestin-independent mechanism. Here we use an iterative,...
13.
Fonzi K, Lefner M, Phillips P, Wanat M
Cell Rep
. 2017 Aug;
20(8):1765-1774.
PMID: 28834741
The dopamine system responds to reward-predictive cues to reflect a prospective estimation of reward value, although its role in encoding retrospective reward-related information is unclear. We report that cue-evoked dopamine...
14.
Rodeberg N, Sandberg S, Johnson J, Phillips P, Wightman R
ACS Chem Neurosci
. 2017 Jan;
8(2):221-234.
PMID: 28127962
Fast-scan cyclic voltammetry (FSCV) has been used for over 20 years to study rapid neurotransmission in awake and behaving animals. These experiments were first carried out with carbon-fiber microelectrodes (CFMs)...
15.
Soden M, Miller S, Burgeno L, Phillips P, Hnasko T, Zweifel L
Cell Rep
. 2016 Jun;
16(2):304-313.
PMID: 27346361
Nearly all animals engage in a complex assortment of social behaviors that are essential for the survival of the species. In mammals, these behaviors are regulated by sub-nuclei within the...
16.
17.
Kishida K, Saez I, Lohrenz T, Witcher M, Laxton A, Tatter S, et al.
Proc Natl Acad Sci U S A
. 2015 Nov;
113(1):200-5.
PMID: 26598677
In the mammalian brain, dopamine is a critical neuromodulator whose actions underlie learning, decision-making, and behavioral control. Degeneration of dopamine neurons causes Parkinson's disease, whereas dysregulation of dopamine signaling is...
18.
Hollon N, Burgeno L, Phillips P
Nat Neurosci
. 2015 Sep;
18(10):1405-12.
PMID: 26404715
Exposure to stress has profound, but complex, actions on motivated behavior and decision-making. These effects are central to core symptoms of a number of psychiatric disorders that are precipitated or...
19.
Ehrich J, Messinger D, Knakal C, Kuhar J, Schattauer S, Bruchas M, et al.
J Neurosci
. 2015 Sep;
35(37):12917-31.
PMID: 26377476
Significance Statement: Kappa opioid receptor (KOR) agonists have the potential to be effective, nonaddictive analgesics, but their therapeutic utility is greatly limited by adverse effects on mood. Understanding how KOR...
20.
Wassum K, Phillips P
ACS Chem Neurosci
. 2014 Dec;
6(1):11-3.
PMID: 25526380
Online electrochemical detection techniques are the state-of-the-art for evaluating chemical communication in the brain underlying motivated behavior and decision making. In this Viewpoint, we discuss avenues for future technological development,...