Larry S Zweifel
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Explore the profile of Larry S Zweifel including associated specialties, affiliations and a list of published articles.
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94
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Recent Articles
1.
Hashikawa K, Hashikawa Y, Briones B, Ishii K, Liu Y, Rossi M, et al.
bioRxiv
. 2025 Mar;
PMID: 40060480
One Sentence Summary: Single cell RNA sequencing reveals how adolescent sex hormones sculpt hypothalamic cell types required for mating behavior.
2.
Qiu J, Talbi R, Bosch M, Medve E, Zweifel L, Ronnekleiv O, et al.
Endocrinology
. 2025 Jan;
166(2).
PMID: 39865886
Hypothalamic kisspeptin (Kiss1) neurons are vital for maintaining fertility in the mammal. In the female rodent, Kiss1 neurons populate the anteroventral periventricular/periventricular nuclei (Kiss1AVPV/PeN) and the arcuate nucleus (Kiss1ARH). Kiss1ARH...
3.
Dai B, Zheng B, Dai X, Cui X, Yin L, Cai J, et al.
Nature
. 2025 Jan;
639(8054):430-437.
PMID: 39843745
Numerous studies support the role of dopamine in modulating aggression, but the exact neural mechanisms remain elusive. Here we show that dopaminergic cells in the ventral tegmental area (VTA) can...
4.
Marcus D, English A, Chun G, Seth E, Oomen R, Hwang S, et al.
bioRxiv
. 2025 Jan;
PMID: 39829909
Neuromodulatory signaling is poised to serve as a neural mechanism for gain control, acting as a crucial tuning factor to influence neuronal activity by dynamically shaping excitatory and inhibitory fast...
5.
Kong M, Ancell E, Witten D, Zweifel L
Elife
. 2025 Jan;
13.
PMID: 39792138
The central amygdala (CeA) has emerged as an important brain region for regulating both negative (fear and anxiety) and positive (reward) affective behaviors. The CeA has been proposed to encode...
6.
Pati D, Taxier L, Xia M, Lee S, Conley S, Sides T, et al.
Addict Neurosci
. 2025 Jan;
11.
PMID: 39741698
Dysregulation of the dopamine (DA) system is a hallmark of substance use disorders, including alcohol use disorder (AUD). Of the DA receptor subtypes, the DA D2 receptors (D2Rs) play a...
7.
Qiu J, Voliotis M, Bosch M, Li X, Zweifel L, Tsaneva-Atanasova K, et al.
Elife
. 2024 Dec;
13.
PMID: 39671233
Hypothalamic kisspeptin (Kiss1) neurons are vital for pubertal development and reproduction. Arcuate nucleus Kiss1 (Kiss1) neurons are responsible for the pulsatile release of gonadotropin-releasing hormone (GnRH). In females, the behavior...
8.
Kielhold M, Jacobs D, Torrado-Pacheco A, Lebowitz J, Langdon A, Williams J, et al.
bioRxiv
. 2024 Nov;
PMID: 39554173
Psychosis is a hallmark of schizophrenia. It typically emerges in late adolescence and is associated with dopamine abnormalities and aberrant salience. Most genes associated with schizophrenia risk involve ubiquitous targets...
9.
Lesuis S, Park S, Hoorn A, Rashid A, Mocle A, Salter E, et al.
Cell
. 2024 Nov;
188(1):121-140.e20.
PMID: 39549697
Stress induces aversive memory overgeneralization, a hallmark of many psychiatric disorders. Memories are encoded by a sparse ensemble of neurons active during an event (an engram ensemble). We examined the...
10.
Kong M, Jo Y, Sethi E, Pyeon G, Zweifel L
bioRxiv
. 2024 Sep;
PMID: 39282301
A positive mental state has been shown to modulate fear-related emotions associated with the recall of fear memories. These, and other observations suggest the presence of central brain mechanisms for...