Paul E Lund
Overview
Explore the profile of Paul E Lund including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
174
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0
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Recent Articles
1.
Hou Q, Chatterjee S, Lund P, Suddala K, Walter N
Nucleic Acids Res
. 2023 Oct;
51(20):11345-11357.
PMID: 37855661
Bacteria live in a broad range of environmental temperatures that require adaptations of their RNA sequences to maintain function. Riboswitches are regulatory RNAs that change conformation upon typically binding metabolite...
2.
Lund P, Chatterjee S, Daher M, Walter N
Nucleic Acids Res
. 2019 Dec;
48(4):2107-2125.
PMID: 31832686
Ribosomal protein S1 plays important roles in the translation initiation step of many Escherichia coli mRNAs, particularly those with weak Shine-Dalgarno sequences or structured 5' UTRs, in addition to a...
3.
Jalihal A, Lund P, Walter N
Cold Spring Harb Perspect Biol
. 2019 Apr;
11(4).
PMID: 30936188
RNAs, across their numerous classes, often work in concert with proteins in RNA-protein complexes (RNPs) to execute critical cellular functions. Ensemble-averaging methods have been instrumental in revealing many important aspects...
4.
Hayward S, Lund P, Kang Q, Johnson-Buck A, Tewari M, Walter N
J Am Chem Soc
. 2018 Aug;
140(37):11755-11762.
PMID: 30125495
Conventional techniques for detecting rare DNA sequences require many cycles of PCR amplification for high sensitivity and specificity, potentially introducing significant biases and errors. While amplification-free methods exist, they rarely...
5.
Rinaldi A, Lund P, Blanco M, Walter N
Nat Commun
. 2016 Jan;
7:8976.
PMID: 26781350
In response to intracellular signals in Gram--negative bacteria, translational riboswitches--commonly embedded in messenger RNAs (mRNAs)-regulate gene expression through inhibition of translation initiation. It is generally thought that this regulation originates...
6.
Bartke R, Cameron E, Cristie-David A, Custer T, DeNies M, Daher M, et al.
Biopolymers
. 2014 Dec;
103(5):296-302.
PMID: 25546606
Four days after the announcement of the 2014 Nobel Prize in Chemistry for "the development of super-resolved fluorescence microscopy" based on single molecule detection, the Single Molecule Analysis in Real-Time...
7.
Fung K, Pan J, Ohnuma S, Lund P, Pixley J, Kimchi-Sarfaty C, et al.
Cancer Res
. 2013 Dec;
74(2):598-608.
PMID: 24305879
The drug efflux function of P-glycoprotein (P-gp) encoded by MDR1 can be influenced by genetic polymorphisms, including two synonymous changes in the coding region of MDR1. Here we report that...
8.
Macadangdang B, Zhang N, Lund P, Marple A, Okabe M, Gottesman M, et al.
PLoS One
. 2011 Mar;
6(3):e17981.
PMID: 21445346
Peptide nucleic acid (PNA) is known to bind with extraordinarily high affinity and sequence-specificity to complementary nucleic acid sequences and can be used to suppress gene expression. However, effective delivery...
9.
Lund P, Hunt R, Gottesman M, Kimchi-Sarfaty C
Pharm Res
. 2009 Dec;
27(3):400-20.
PMID: 19998056
Over the last two decades, small interfering RNA (siRNA)-mediated gene silencing has quickly become one of the most powerful techniques used to study gene function in vitro and a promising...