Paul E Clavijo
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Explore the profile of Paul E Clavijo including associated specialties, affiliations and a list of published articles.
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29
Citations
1160
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Recent Articles
1.
Morgan E, Saleh A, Cornelius S, Carlson S, Toni T, Cheng H, et al.
Cancer Res Commun
. 2024 Oct;
4(11):2903-2918.
PMID: 39392349
Here, RNAi library screening reveals that multiple G2/M and kinetochore components, including TTK/monopolar spindle 1, modulate TNFα-induced NF-κB activation, cell survival, and genotoxicity, underscoring their potential importance as therapeutic targets...
2.
Fay M, Clavijo P, Allen C
Head Neck
. 2024 Apr;
46(10):2591-2599.
PMID: 38622975
Background: Neutrophilic cells are among the most abundant immune populations within the head and neck tumor microenvironment (TME) and harbor multiple mechanisms of immunosuppression. Despite these important features, neutrophilic cells...
3.
Quantification and Functional Studies of Neutrophilic Cells Identifies Distinct Papilloma Phenotypes
Bai K, Clavijo P, Robbins Y, Norberg S, Allen C
Laryngoscope
. 2024 Mar;
134(7):3238-3244.
PMID: 38436434
Objectives: To characterize the distribution of immune cell subsets within laryngeal papillomas and to study the function of potentially immunosuppressive neutrophilic and regulatory T cells (Tregs). Methods: Fresh clinical papilloma...
4.
Sakakibara N, Clavijo P, Sievers C, Gray V, King K, George A, et al.
Front Immunol
. 2023 Aug;
14:1200970.
PMID: 37638000
Introduction: Amplification of human chromosome 3q26-29, which encodes oncoprotein ΔNp63 among other isoforms of the p63 family, is a feature common to squamous cell carcinomas (SCCs) of multiple tissue origins....
5.
Sievers C, Robbins Y, Bai K, Yang X, Clavijo P, Friedman J, et al.
Commun Biol
. 2021 Dec;
4(1):1416.
PMID: 34931021
Recurrent respiratory papillomatosis (RRP) is a debilitating neoplastic disorder of the upper aerodigestive tract caused by chronic infection with low-risk human papillomavirus types 6 or 11. Patients with severe RRP...
6.
Valencia J, Erwin-Cohen R, Clavijo P, Allen C, Sanford M, Day C, et al.
Cancer Res
. 2021 Oct;
81(23):5977-5990.
PMID: 34642183
The relationship between cancer and autoimmunity is complex. However, the incidence of solid tumors such as melanoma has increased significantly among patients with previous or newly diagnosed systemic autoimmune disease...
7.
Robbins Y, Friedman J, Clavijo P, Sievers C, Bai K, Donahue R, et al.
J Immunother Cancer
. 2021 Aug;
9(8).
PMID: 34462327
Background: Recurrent respiratory papillomatosis (RRP) is a human papillomavirus (HPV) driven neoplastic disorder of the upper aerodigestive tract that causes significant morbidity and can lead to fatal airway obstruction. Prior...
8.
Lee M, Robbins Y, Sievers C, Friedman J, Sater H, Clavijo P, et al.
J Immunother Cancer
. 2021 Mar;
9(3).
PMID: 33741731
Background: As heterogeneous tumors develop in the face of intact immunity, tumor cells harboring genomic or expression defects that favor evasion from T-cell detection or elimination are selected. For patients...
9.
Robbins Y, Greene S, Friedman J, Clavijo P, Van Waes C, Fabian K, et al.
Elife
. 2020 Jul;
9.
PMID: 32633234
Failed T cell-based immunotherapies in the presence of genomic alterations in antigen presentations pathways may be overcome by NK cell-based immunotherapy. This approach may still be limited by the presence...
10.
Ye W, Gunti S, Allen C, Hong Y, Clavijo P, Van Waes C, et al.
Oncoimmunology
. 2020 Feb;
9(1):1710398.
PMID: 32002309
Inhibitor of apoptosis protein (IAP) antagonists have shown activity in preclinical models of head and neck squamous cell carcinoma (HNSCC), and work across several cancer types has demonstrated diverse immune...