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Paul D Hartley

Explore the profile of Paul D Hartley including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 1642
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Recent Articles
1.
Khan M, Li L, Haak L, Payen S, Carine M, Adhikari K, et al.
One Health . 2023 Apr; 16:100536. PMID: 37041760
Detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral genome in wastewater has proven to be useful for tracking the trends of virus prevalence within the community. The surveillance...
2.
Li L, Uppal T, Hartley P, Gorzalski A, Pandori M, Picker M, et al.
Sci Rep . 2022 Sep; 12(1):16141. PMID: 36167869
Detection of SARS-CoV-2 viral load in wastewater has been highly informative in estimating the approximate number of infected individuals in the surrounding communities. Recent developments in wastewater monitoring to determine...
3.
Li L, Uppal T, Hartley P, Gorzalski A, Pandori M, Picker M, et al.
Res Sq . 2022 Mar; PMID: 35313589
Detection of SARS-CoV-2 viral load in wastewater has been highly informative in estimating the approximate number of infected individuals in the surrounding communities. Recent developments in wastewater monitoring to determine...
4.
Hartley P, Tillett R, AuCoin D, Sevinsky J, Xu Y, Gorzalski A, et al.
J Genet Genomics . 2021 Apr; 48(1):40-51. PMID: 33820739
Patients with signs of COVID-19 were tested through diagnostic RT-PCR for SARS-CoV-2 using RNA extracted from the nasopharyngeal/nasal swabs. To determine the variants of SARS-CoV-2 circulating in the state of...
5.
Tillett R, Sevinsky J, Hartley P, Kerwin H, Crawford N, Gorzalski A, et al.
Lancet Infect Dis . 2020 Oct; 21(1):52-58. PMID: 33058797
Background: The degree of protective immunity conferred by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently unknown. As such, the possibility of reinfection with SARS-CoV-2 is not...
6.
Hartley P, Tillett R, AuCoin D, Sevinsky J, Xu Y, Gorzalski A, et al.
medRxiv . 2020 Sep; PMID: 32869037
Patients with signs of COVID-19 were tested with CDC approved diagnostic RT-PCR for SARS-CoV-2 using RNA extracted from nasopharyngeal/nasal swabs. In order to determine the variants of SARS-CoV-2 circulating in...
7.
Troll C, Putnam N, Hartley P, Rice B, Blanchette M, Siddiqui S, et al.
J Mol Diagn . 2019 Jan; 21(3):375-383. PMID: 30605765
The clinical management and therapy of many solid tumor malignancies depends on detection of medically actionable or diagnostically relevant genetic variation. However, a principal challenge for genetic assays from tumors...
8.
Putnam N, OConnell B, Stites J, Rice B, Blanchette M, Calef R, et al.
Genome Res . 2016 Feb; 26(3):342-50. PMID: 26848124
Long-range and highly accurate de novo assembly from short-read data is one of the most pressing challenges in genomics. Recently, it has been shown that read pairs generated by proximity...
9.
Kim D, Kwon E, Hartley P, Crosby D, Mann S, Krogan N, et al.
Mol Cell . 2013 Jan; 49(4):632-44. PMID: 23333304
The HIV-1 accessory protein Vif hijacks a cellular Cullin-RING ubiquitin ligase, CRL5, to promote degradation of the APOBEC3 (A3) family of restriction factors. Recently, the cellular transcription cofactor CBFβ was...
10.
Gleason E, Hartley P, Henderson M, Hill-Harfe K, Price P, Weimer R, et al.
Genetics . 2012 Mar; 191(2):477-91. PMID: 22446317
Secretory vesicles are used during spermatogenesis to deliver proteins to the cell surface. In Caenorhabditis elegans, secretory membranous organelles (MO) fuse with the plasma membrane to transform spermatids into fertilization-competent...