Paul B Talbert
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Explore the profile of Paul B Talbert including associated specialties, affiliations and a list of published articles.
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37
Citations
2621
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Recent Articles
11.
Talbert P, Henikoff S
J Cell Sci
. 2021 Mar;
134(6).
PMID: 33771851
Eukaryotic nucleosomes organize chromatin by wrapping 147 bp of DNA around a histone core particle comprising two molecules each of histone H2A, H2B, H3 and H4. The DNA entering and...
12.
Talbert P, Henikoff S
Exp Cell Res
. 2020 Feb;
389(2):111895.
PMID: 32035948
Centromeres are the eukaryotic chromosomal sites at which the kinetochore forms and attaches to spindle microtubules to orchestrate chromosomal segregation in mitosis and meiosis. Although centromeres are essential for cell...
13.
Talbert P, Meers M, Henikoff S
Nat Rev Genet
. 2019 Mar;
20(5):283-297.
PMID: 30886348
Sophisticated gene-regulatory mechanisms probably evolved in prokaryotes billions of years before the emergence of modern eukaryotes, which inherited the same basic enzymatic machineries. However, the epigenomic landscapes of eukaryotes are...
14.
Talbert P, Henikoff S
Trends Genet
. 2018 Jun;
34(8):587-599.
PMID: 29871772
Chromosome segregation depends on the attachment of spindle microtubules to sites on chromosomal DNA known as centromeres, through kinetochore protein complexes. Although RNA was found in kinetochores in the 1970s,...
15.
Talbert P, Kasinathan S, Henikoff S
Genetics
. 2018 Jan;
208(3):977-990.
PMID: 29305387
Centromeres are the chromosomal sites of assembly for kinetochores, the protein complexes that attach to spindle fibers and mediate separation of chromosomes to daughter cells in mitosis and meiosis. In...
16.
Henikoff S, Thakur J, Kasinathan S, Talbert P
Cold Spring Harb Symp Quant Biol
. 2017 Dec;
82:71-82.
PMID: 29196559
Centromeres were familiar to cell biologists in the late 19th century, but for most eukaryotes the basis for centromere specification has remained enigmatic. Much attention has been focused on the...
17.
Talbert P, Henikoff S
Nat Rev Mol Cell Biol
. 2016 Dec;
18(2):115-126.
PMID: 27924075
Most histones are assembled into nucleosomes behind the replication fork to package newly synthesized DNA. By contrast, histone variants, which are encoded by separate genes, are typically incorporated throughout the...
18.
Draizen E, Shaytan A, Marino-Ramirez L, Talbert P, Landsman D, Panchenko A
Database (Oxford)
. 2016 Mar;
2016.
PMID: 26989147
Compaction of DNA into chromatin is a characteristic feature of eukaryotic organisms. The core (H2A, H2B, H3, H4) and linker (H1) histone proteins are responsible for this compaction through the...
19.
Thakur J, Talbert P, Henikoff S
Genetics
. 2015 Aug;
201(2):543-61.
PMID: 26275423
Centromeres of the fission yeast Schizosaccharomyces pombe lack the highly repetitive sequences that make most other "regional" centromeres refractory to analysis. To map fission yeast centromeres, we applied H4S47C-anchored cleavage...
20.
Talbert P, Henikoff S
Trends Cell Biol
. 2014 Aug;
24(11):642-50.
PMID: 25150594
Fluctuations in the ambient environment can trigger chromatin disruptions, involving replacement of nucleosomes or exchange of their histone subunits. Unlike canonical histones, which are available only during S-phase, replication-independent histone...