Paul A White
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Explore the profile of Paul A White including associated specialties, affiliations and a list of published articles.
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123
Citations
1740
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Recent Articles
1.
Schuster D, LeBlanc D, Zhou G, Meier M, Dodge A, White P, et al.
Environ Sci Technol
. 2024 Nov;
58(49):21450-21463.
PMID: 39602390
Polycyclic aromatic hydrocarbons (PAHs) are common environmental pollutants that originate from the incomplete combustion of organic materials. We investigated the clastogenicity and mutagenicity of benzo[]fluoranthene (BbF), one of 16 priority...
2.
Papas W, Aranda-Rodriguez R, Fan X, Kubwabo C, Lee J, Fantin E, et al.
Toxics
. 2024 Sep;
12(9).
PMID: 39330605
Firefighters can be exposed to complex mixtures of airborne substances, including hazardous substances released during structural fires. This study employed silicone wristbands (SWBs) as passive samplers to investigate potential exposure...
3.
Parsons B, Beal M, Dearfield K, Douglas G, Gi M, Gollapudi B, et al.
Environ Mol Mutagen
. 2024 Jun;
PMID: 38828778
Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose-response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An...
4.
Beal M, Chen G, Dearfield K, Gi M, Gollapudi B, Heflich R, et al.
Environ Mol Mutagen
. 2023 Dec;
PMID: 38115239
Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non-animal approaches can be human-relevant alternatives. There is an urgent...
5.
Keir J, Papas W, Wawrzynczak A, Aranda-Rodriguez R, Blais J, White P
Environ Res
. 2023 Oct;
239(Pt 1):117306.
PMID: 37797669
Firefighters experience exposures to carcinogenic and mutagenic substances, including polycyclic aromatic hydrocarbons (PAHs). Silicone wristbands (SWBs) have been used as passive samplers to assess firefighters' exposures over the course of...
6.
Fortin A, Long A, Williams A, Meier M, Cox J, Pinsonnault C, et al.
Front Toxicol
. 2023 Feb;
5:1098432.
PMID: 36756349
The conventional battery for genotoxicity testing is not well suited to assessing the large number of chemicals needing evaluation. Traditional tests lack throughput, provide little mechanistic information, and have poor...
7.
Keir J, Kirkham T, Aranda-Rodriguez R, White P, Blais J
J Occup Environ Hyg
. 2022 Dec;
20(2):84-94.
PMID: 36469739
Firefighters are exposed to carcinogenic and mutagenic combustion emissions, including polycyclic aromatic hydrocarbons (PAHs). Fire service and firefighter cancer advocacy groups recommend skin cleaning using wipes or washing with detergent...
8.
Demers P, DeMarini D, Fent K, Glass D, Hansen J, Adetona O, et al.
Lancet Oncol
. 2022 Jul;
23(8):985-986.
PMID: 35780778
No abstract available.
9.
Kuo B, Beal M, Wills J, White P, Marchetti F, Nong A, et al.
Arch Toxicol
. 2022 Apr;
96(7):2067-2085.
PMID: 35445829
Risk assessments are increasingly reliant on information from in vitro assays. The in vitro micronucleus test (MNvit) is a genotoxicity test that detects chromosomal abnormalities, including chromosome breakage (clastogenicity) and/or...
10.
Marchetti F, Zhou G, LeBlanc D, White P, Williams A, Yauk C, et al.
Arch Toxicol
. 2021 Jan;
95(3):1103-1116.
PMID: 33506374
The Organisation for Economic Co-Operation and Development Test Guideline 488 (TG 488) uses transgenic rodent models to generate in vivo mutagenesis data for regulatory submission. The recommended design in TG...