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Andrew Williams

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Articles 400
Citations 5269
Followers 0
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Recent Articles
1.
Stead J, Lee H, Williams A, Ramirez S, Atlas E, Mennigen J, et al.
Bioinform Biol Insights . 2025 Mar; 19:11779322251321071. PMID: 40040651
High-throughput gene expression studies commonly employ pathway analyses to infer biological meaning from lists of differentially expressed genes (DEGs). In toxicology and pharmacology studies, treatment groups are analysed against vehicle...
2.
LeBlanc D, Zhou G, Williams A, Meier M, Valentine C, Salk J, et al.
Biol Reprod . 2025 Feb; PMID: 39936590
Germ cell mutagenicity testing is increasingly required for chemical risk assessment. Duplex Sequencing (DS) is rapidly gaining acceptance as a method to assess in vivo mutagenesis, and as a valid...
3.
Renaud J, Muir B, Williams A, McEwen M
Med Phys . 2025 Feb; PMID: 39904607
Background: Ultra-high dose rate radiotherapy (UHDR) delivers therapeutic doses at rates >40 Gy/s in a fraction of a second, aiming to enhance the therapeutic ratio through the FLASH effect. The...
4.
Natarajan R, ODell F, Mant M, Williams A
Arch Dis Child . 2025 Feb; PMID: 39904569
No abstract available.
5.
Q Vuong N, Khilji S, Williams A, Adam N, Flores D, Fulton K, et al.
Int J Radiat Biol . 2025 Jan; 101(3):240-253. PMID: 39746153
Background: Recent advancements in omics and benchmark dose (BMD) modeling have facilitated identifying the dose required for a predetermined change in a response (e.g. gene or protein change) that can...
6.
Axelsson J, LeBlanc D, Shojaeisaadi H, Meier M, Fitzgerald D, Nachmanson D, et al.
Sci Rep . 2024 Dec; 14(1):30571. PMID: 39702384
No abstract available.
7.
Luijten M, van Benthem J, Morita T, Corvi R, Escobar P, Fujita Y, et al.
Environ Mol Mutagen . 2024 Dec; PMID: 39628086
In human health risk assessment of chemicals and pharmaceuticals, identification of genotoxicity hazard usually starts with a standard battery of in vitro genotoxicity tests, which is needed to cover all...
8.
Schuster D, LeBlanc D, Zhou G, Meier M, Dodge A, White P, et al.
Environ Sci Technol . 2024 Nov; 58(49):21450-21463. PMID: 39602390
Polycyclic aromatic hydrocarbons (PAHs) are common environmental pollutants that originate from the incomplete combustion of organic materials. We investigated the clastogenicity and mutagenicity of benzo[]fluoranthene (BbF), one of 16 priority...
9.
Connaughton S, Williams A, Gardner G
Meat Sci . 2024 Nov; 220:109707. PMID: 39532034
Dual Energy X-ray Absorptiometry (DXA) scanners operating at abattoir processing speeds are currently installed in six sheep meat abattoirs around Australia, predicting carcass composition as estimates of computed tomography (CT)...
10.
Shojaeisaadi H, Schoenrock A, Meier M, Williams A, Norris J, Palmer N, et al.
Commun Biol . 2024 Nov; 7(1):1451. PMID: 39506086
Whole-genome sequencing studies of parent-offspring trios have provided valuable insights into the potential impact of de novo mutations (DNMs) on human health and disease. However, the molecular mechanisms that drive...