Paul A Smith
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Explore the profile of Paul A Smith including associated specialties, affiliations and a list of published articles.
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154
Citations
2483
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Recent Articles
11.
Reeve C, Robichaud J, Fernandes T, Bates A, Bramburger A, Brownscombe J, et al.
Conserv Physiol
. 2023 May;
11(1):coad027.
PMID: 37179705
Winter at high latitudes is characterized by low temperatures, dampened light levels and short photoperiods which shape ecological and evolutionary outcomes from cells to populations to ecosystems. Advances in our...
12.
Anderson C, Fahrig L, Rausch J, Martin J, Daufresne T, Smith P
Ecol Evol
. 2023 Feb;
13(2):e9797.
PMID: 36778838
Aim: To test whether the occupancy of shorebirds has changed in the eastern Canadian Arctic, and whether these changes could indicate that shorebird distributions are shifting in response to long-term...
13.
Flemming S, Smith P, Kennedy L, Anderson A, Nol E
PLoS One
. 2022 Jul;
17(7):e0269938.
PMID: 35776726
Over the last 60 years, Arctic goose populations have increased while many sympatric tundra nesting bird populations have declined. Hyperabundant geese have well-documented effects on tundra habitats, which can alter...
14.
Anderson A, Friis C, Gratto-Trevor C, Harris C, Love O, Morrison R, et al.
Oecologia
. 2021 Oct;
197(3):661-674.
PMID: 34657196
Droughts can affect invertebrate communities in wetlands, which can have bottom-up effects on the condition and survival of top predators. Shorebirds, key predators at coastal wetlands, have experienced widespread population...
15.
Scuron M, Fay B, Connell A, Oliver J, Smith P
Int Immunopharmacol
. 2021 Jul;
98:107904.
PMID: 34214886
Dysregulation of phosphoinositide 3-kinase δ (PI3Kδ) signaling pathway has been implicated in the pathogenesis of inflammatory and autoimmune diseases. Parsaclisib (INCB050465) represents a potent and selective PI3Kδ inhibitor, which is...
16.
Huarte E, Peel M, Verbist K, Fay B, Bassett R, Albeituni S, et al.
Front Pharmacol
. 2021 May;
12:650295.
PMID: 33981229
Hyperinflammatory syndromes comprise a heterogeneous group of disorders characterized by severe inflammation, multiple organ dysfunction, and potentially death. In response to antigenic stimulus (e.g., SARS-CoV-2 infection), overactivated CD8+ T-cells and...
17.
Teng B, Hayasaka Y, Smith P, Bindon K
J Agric Food Chem
. 2021 Apr;
69(16):4804-4815.
PMID: 33853320
This study aimed to assess the effect of tannin molecular mass on nonbleachable pigment formation and subsequent stability under wine-like conditions. Tannin fractions of a defined molecular mass range were...
18.
Scuron M, Fay B, Connell A, Peel M, Smith P
Front Immunol
. 2021 Mar;
11:620098.
PMID: 33658996
The goal of this study was to elucidate the anti-pruritic and anti-inflammatory efficacy of ruxolitinib cream in experimentally-induced dermatitis. Atopic dermatitis (AD), the most common chronic relapsing inflammatory skin disease,...
19.
Saarti M, Almukhtar H, Smith P, Roberts R
Eur J Pharmacol
. 2021 Feb;
896:173917.
PMID: 33529727
In order to gain insight into the regulation of vascular tone by mitochondria, the effects of mitochondrial complex III inhibitors on contractile responses in porcine isolated coronary arteries were investigated....
20.
Huarte E, OConnor R, Peel M, Nunez-Cruz S, Leferovich J, Juvekar A, et al.
Clin Cancer Res
. 2020 Oct;
26(23):6299-6309.
PMID: 32998963
Purpose: T cells engineered to express a chimeric antigen receptor (CAR) are a promising cancer immunotherapy. Such targeted therapies have shown long-term relapse-free survival in patients with B-cell leukemia and...