Patrizia Hrelia
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Explore the profile of Patrizia Hrelia including associated specialties, affiliations and a list of published articles.
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166
Citations
2271
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Recent Articles
21.
Lenzi M, Gasperini S, Cocchi V, Tirri M, Marti M, Hrelia P
Int J Mol Sci
. 2022 May;
23(10).
PMID: 35628658
The novel psychoactive substance (NPS) 4-Methyl-5-(4-methylphenyl)-4,5-dihydroxazol-2-amine (4,4'-DMAR) shows psychostimulant activity. Data on the acute toxicity of 4,4'-DMAR are becoming increasingly available, yet the long-term effects are still almost unknown. In...
22.
Ravegnini G, Hrelia P, Angelini S
Cancer Drug Resist
. 2022 May;
2(1):107-115.
PMID: 35582147
Gastrointestinal stromal tumors (GISTs) are rare entities, which, however, represent the most common mesenchymal tumor of the gastrointestinal tract. The discovery of gain of function mutations on and receptor genes...
23.
Lampis S, Raieli S, Montemurro L, Bartolucci D, Amadesi C, Bortolotti S, et al.
J Exp Clin Cancer Res
. 2022 Apr;
41(1):160.
PMID: 35490242
Background: Neuroblastoma is a deadly childhood cancer, and MYCN-amplified neuroblastoma (MNA-NB) patients have the worst prognoses and are therapy-resistant. While retinoic acid (RA) is beneficial for some neuroblastoma patients, the...
24.
Ravegnini G, De Leo A, Coada C, Gorini F, de Biase D, Ceccarelli C, et al.
Front Oncol
. 2021 Nov;
11:757678.
PMID: 34804952
Introduction: The Cancer Genome Atlas (TCGA) project identified four distinct prognostic groups in endometrial cancer (EC), among which two are correlated with an intermediate prognosis: the MisMatch Repair-deficient (MMRd) and...
25.
Ravegnini G, Gorini F, De Crescenzo E, De Leo A, de Biase D, Di Stanislao M, et al.
Int J Cancer
. 2021 Oct;
150(7):1077-1090.
PMID: 34706070
Endometrial cancer (EC) is the most common gynecological cancer, with annual incidence rates in Western countries ranging between 15 and 25 per 100 000 women. About 15% to 20% of...
26.
Sita G, Graziosi A, Hrelia P, Morroni F
Int J Mol Sci
. 2021 Oct;
22(20).
PMID: 34681862
Glioblastoma multiforme (GBM) is the most prevalent and aggressive primary brain tumor. The median survival rate from diagnosis ranges from 15 to 17 months because the tumor is resistant to...
27.
Ravegnini G, De Iaco P, Gorini F, Dondi G, Klooster I, De Crescenzo E, et al.
Biomedicines
. 2021 Oct;
9(10).
PMID: 34680433
Epithelial ovarian cancer (EOC) is one of the most lethal cancers worldwide, mostly due to nonspecific symptoms and a lack of screening tests, which, taken together, contribute to delayed diagnosis...
28.
Sita G, Graziosi A, Hrelia P, Morroni F
Int J Mol Sci
. 2021 Jul;
22(13).
PMID: 34209586
Amyloid beta (Aβ)-induced abnormal neuroinflammation is recognized as a major pathological feature of Alzheimer's disease (AD), which results in memory impairment. Research exploring low-grade systemic inflammation and its impact on...
29.
Evaluation of Cytotoxic and Mutagenic Effects of the Synthetic Cathinones Mexedrone, α-PVP and α-PHP
Lenzi M, Cocchi V, Gasperini S, Arfe R, Marti M, Hrelia P
Int J Mol Sci
. 2021 Jul;
22(12).
PMID: 34204826
Mexedrone, α-PVP and α-PHP are synthetic cathinones. They can be considered amphetamine-like substances with a stimulating effect. Actually, studies showing their impact on DNA are totally absent. Therefore, in order...
30.
Raieli S, Di Renzo D, Lampis S, Amadesi C, Montemurro L, Pession A, et al.
Front Oncol
. 2021 Mar;
11:625207.
PMID: 33718189
A wide range of malignancies presents amplification (MNA) or dysregulation. is associated with poor prognosis and its over-expression leads to several dysregulations including metabolic reprogramming, mitochondria alteration, and cancer stem...