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Patrick Voskamp

Explore the profile of Patrick Voskamp including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 70
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Saberi M, Chikunova A, Ben Bdira F, Cramer-Blok A, Timmer M, Voskamp P, et al.
FEBS J . 2024 Aug; 291(19):4222-4239. PMID: 39185686
Bacillus circulans xylanase (BcX) from the glycoside hydrolase family 11 degrades xylan through a retaining, double-displacement mechanism. The enzyme is thought to hydrolyze glycosidic bonds in a processive manner and...
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Sun J, Chikunova A, Boyle A, Voskamp P, Timmer M, Ubbink M
Int J Biol Macromol . 2023 Aug; 250:126160. PMID: 37549761
The β-lactamase BlaC conveys resistance to a broad spectrum of β-lactam antibiotics to its host Mycobacterium tuberculosis but poorly hydrolyzes third-generation cephalosporins, such as ceftazidime. Variants of other β-lactamases have...
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Rashid F, Mahlandt E, van der Vaart M, Boer D, Varela Alvarez M, Henneman B, et al.
Nucleic Acids Res . 2021 Nov; 50(2):e10. PMID: 34734265
The interplay between three-dimensional chromosome organisation and genomic processes such as replication and transcription necessitates in vivo studies of chromosome dynamics. Fluorescent organic dyes are often used for chromosome labelling...
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Xiao X, Willemse J, Voskamp P, Li X, Prota A, Lamers M, et al.
Open Biol . 2021 Feb; 11(2):200409. PMID: 33622102
In most bacteria, cell division begins with the polymerization of the GTPase FtsZ at mid-cell, which recruits the division machinery to initiate cell constriction. In the filamentous bacterium , cell...
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Boyle A, Rabe M, Crone N, Rhys G, Soler N, Voskamp P, et al.
Chem Sci . 2019 Sep; 10(31):7456-7465. PMID: 31489168
Designing peptides that fold and assemble in response to metal ions tests our understanding of how peptide folding and metal binding influence one another. Here, histidine residues are introduced into...
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Kytidou K, Beekwilder J, Artola M, van Meel E, Wilbers R, Moolenaar G, et al.
J Biol Chem . 2018 Apr; 293(26):10042-10058. PMID: 29674318
α-Galactosidases (EC 3.2.1.22) are retaining glycosidases that cleave terminal α-linked galactose residues from glycoconjugate substrates. α-Galactosidases take part in the turnover of cell wall-associated galactomannans in plants and in the...
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Dijk M, Holkers J, Voskamp P, Giannetti B, Waterreus W, van Veen H, et al.
Structure . 2016 Nov; 24(12):2182-2189. PMID: 27818099
C1-inhibitor is a key inhibitor of the complement and contact activation systems, and mutations in the protein can cause hereditary angioedema. Through an unknown mechanism, polysaccharides can increase C1-inhibitor activity...
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Backendorf C, Visser A, De Boer A, Zimmerman R, Visser M, Voskamp P, et al.
Annu Rev Pharmacol Toxicol . 2007 Sep; 48:143-69. PMID: 17848136
The avian virus-derived protein apoptin induces p53-independent apoptosis in a tumor-specific way. Apoptin acts as a multimeric complex and forms superstructures upon binding to DNA. In tumor cells, apoptin is...