Patrick T Bunn
Overview
Explore the profile of Patrick T Bunn including associated specialties, affiliations and a list of published articles.
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19
Citations
599
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Recent Articles
1.
Ng S, De Labastida Rivera F, Yan J, Corvino D, Das I, Zhang P, et al.
Nat Immunol
. 2024 Feb;
25(4):716.
PMID: 38360937
No abstract available.
2.
Wang Y, De Labastida Rivera F, Edwards C, Frame T, Engel J, Bukali L, et al.
J Clin Invest
. 2023 Oct;
133(19).
PMID: 37781920
The development of highly effective malaria vaccines and improvement of drug-treatment protocols to boost antiparasitic immunity are critical for malaria elimination. However, the rapid establishment of parasite-specific immune regulatory networks...
3.
Edwards C, Ng S, De Labastida Rivera F, Corvino D, Engel J, Montes de Oca M, et al.
J Clin Invest
. 2023 Feb;
133(4).
PMID: 36787259
No abstract available.
4.
Edwards C, Ng S, De Labastida Rivera F, Corvino D, Engel J, Montes de Oca M, et al.
J Clin Invest
. 2023 Jan;
133(1).
PMID: 36594463
Control of intracellular parasites responsible for malaria requires host IFN-γ+T-bet+CD4+ T cells (Th1 cells) with IL-10 produced by Th1 cells to mitigate the pathology induced by this inflammatory response. However,...
5.
Ng S, De Labastida Rivera F, Yan J, Corvino D, Das I, Zhang P, et al.
Nat Immunol
. 2020 Aug;
21(10):1205-1218.
PMID: 32839608
Immune-modulating therapies have revolutionized the treatment of chronic diseases, particularly cancer. However, their success is restricted and there is a need to identify new therapeutic targets. Here, we show that...
6.
Kumar R, Bunn P, Singh S, Ng S, Montes de Oca M, De Labastida Rivera F, et al.
Cell Rep
. 2020 Feb;
30(8):2512-2525.e9.
PMID: 32101732
Type I interferons (IFNs) play critical roles in anti-viral and anti-tumor immunity. However, they also suppress protective immune responses in some infectious diseases. Here, we identify type I IFNs as...
7.
Bunn P, Montes de Oca M, De Labastida Rivera F, Kumar R, Ng S, Edwards C, et al.
J Immunol
. 2018 Oct;
201(11):3362-3372.
PMID: 30355785
The outcome of intracellular parasitic infection can be determined by the immunoregulatory activities of natural regulatory CD4 Foxp3 T (Treg) cells and the anti-inflammatory cytokine IL-10. These mechanisms protect tissue...
8.
Ng S, Souza-Fonseca-Guimaraes F, De Labastida Rivera F, Amante F, Kumar R, Gao Y, et al.
Clin Transl Immunology
. 2018 Feb;
7(1):e1003.
PMID: 29484181
Objectives: Innate lymphoid cells (ILCs) share many characteristics with CD4 T cells, and group 1 ILCs share a requirement for T-bet and the ability to produce IFNγ with T helper...
9.
Bunn P, Montes de Oca M, De Labastida Rivera F, Kumar R, Edwards C, Faleiro R, et al.
Front Immunol
. 2017 Oct;
8:1307.
PMID: 29075269
Many infectious diseases are characterized by the development of immunoregulatory pathways that contribute to pathogen persistence and associated disease symptoms. In diseases caused by intracellular parasites, such as visceral leishmaniasis...
10.
Lonnberg T, Svensson V, James K, Fernandez-Ruiz D, Sebina I, Montandon R, et al.
Sci Immunol
. 2017 Mar;
2(9).
PMID: 28345074
Differentiation of naïve CD4 T cells into functionally distinct T helper subsets is crucial for the orchestration of immune responses. Due to extensive heterogeneity and multiple overlapping transcriptional programs in...