Patrick Osei-Owusu
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Explore the profile of Patrick Osei-Owusu including associated specialties, affiliations and a list of published articles.
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38
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451
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Recent Articles
1.
Khan S, Gaivin R, Liu Z, Li V, Samuels I, Son J, et al.
bioRxiv
. 2025 Feb;
PMID: 39975070
Graphical Abstract:
2.
Garcia Y, Sjogren B, Osei-Owusu P
Am J Physiol Heart Circ Physiol
. 2025 Jan;
328(2):H348-H360.
PMID: 39772618
Regulators of G protein signaling (RGS) proteins fine-tune signaling via heterotrimeric G proteins to maintain physiologic homeostasis in various organ systems of the human body including the brain, kidney, heart,...
3.
Dahlen S, Mohanty I, Sun B, Nallapaneni S, Osei-Owusu P
Physiol Rep
. 2025 Jan;
13(1):e70178.
PMID: 39746869
Sympathoexcitation is a hallmark of heart failure, with sustained β-adrenergic receptor (βAR)-G protein signaling activation. βAR signaling is modulated by regulator of G protein signaling (RGS) proteins. Previously, we reported...
4.
Sun B, Smith N, Dixon A, Osei-Owusu P
Function (Oxf)
. 2024 Mar;
5(2):zqae003.
PMID: 38486977
G protein regulation by regulators of G protein signaling (RGS) proteins play a key role in vascular tone maintenance. The loss of G and G regulation by RGS2 and RGS5...
5.
Preston K, Kawai T, Torimoto K, Kuroda R, Nakayama Y, Akiyama T, et al.
Hypertens Res
. 2024 Feb;
47(5):1338-1349.
PMID: 38383894
Mitochondrial dysfunction has been implicated in various types of cardiovascular disease including hypertension. Mitochondrial fission fusion balance is critical to mitochondrial quality control, whereas enhanced fission has been reported in...
6.
Eguchi S, Torimoto K, Adebiyi A, Kanthakumar P, Bomfim G, Wenceslau C, et al.
Hypertension
. 2024 Feb;
81(5):977-990.
PMID: 38372140
To celebrate 100 years of American Heart Association-supported cardiovascular disease research, this review article highlights milestone papers that have significantly contributed to the current understanding of the signaling mechanisms driving...
7.
Wei D, Birla H, Dou Y, Mei Y, Huo X, Whitehead V, et al.
J Neurosci
. 2023 Nov;
44(1).
PMID: 37952941
Peripheral sensitization is one of the primary mechanisms underlying the pathogenesis of chronic pain. However, candidate molecules involved in peripheral sensitization remain incompletely understood. We have shown that store-operated calcium...
8.
Dixon A, Osei-Owusu P
Front Physiol
. 2023 May;
14:1141094.
PMID: 37179824
Age-related decline in functional elastin is associated with increased arterial stiffness, a known risk factor for developing cardiovascular disease. While the contribution of elastin insufficiency to the stiffening of conduit...
9.
Randolph C, Dwyer M, Aumiller J, Dixon A, Inoue A, Osei-Owusu P, et al.
J Biol Chem
. 2022 Sep;
298(11):102538.
PMID: 36174676
Heterotrimeric G proteins couple activated G protein-coupled receptors (GPCRs) to intracellular signaling pathways. They can also function independently of GPCR activation upon acquiring mutations that prevent GTPase activity and result...
10.
Fernandes S, Oatman E, Weinberger J, Dixon A, Osei-Owusu P, Hou S
Exp Neurol
. 2022 Aug;
357:114200.
PMID: 35952765
High-level spinal cord injury (SCI) often interrupts supraspinal regulation of sympathetic input to the heart. Although it is known that dysregulated autonomic control increases the risk for cardiac disorders, the...