Patrick L Bader
Overview
Explore the profile of Patrick L Bader including associated specialties, affiliations and a list of published articles.
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5
Citations
534
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Recent Articles
1.
Portmann T, Yang M, Mao R, Panagiotakos G, Ellegood J, Dolen G, et al.
Cell Rep
. 2014 May;
7(4):1077-1092.
PMID: 24794428
A deletion on human chromosome 16p11.2 is associated with autism spectrum disorders. We deleted the syntenic region on mouse chromosome 7F3. MRI and high-throughput single-cell transcriptomics revealed anatomical and cellular...
2.
Owen S, Tuncdemir S, Bader P, Tirko N, Fishell G, Tsien R
Nature
. 2013 Aug;
500(7463):458-62.
PMID: 23913275
Neuromodulatory control by oxytocin is essential to a wide range of social, parental and stress-related behaviours. Autism spectrum disorders (ASD) are associated with deficiencies in oxytocin levels and with genetic...
3.
Faizi M, Bader P, Saw N, Nguyen T, Beraki S, Wyss-Coray T, et al.
Brain Behav
. 2012 May;
2(2):142-54.
PMID: 22574282
Alzheimer's disease (AD), the most common form of dementia, is an age-dependent progressive neurodegenerative disorder. β-amyloid, a metabolic product of the amyloid precursor protein (APP), plays an important role in...
4.
Bader P, Faizi M, Kim L, Owen S, Tadross M, Alfa R, et al.
Proc Natl Acad Sci U S A
. 2011 Sep;
108(37):15432-7.
PMID: 21878566
Autism and autism spectrum disorder (ASD) typically arise from a mixture of environmental influences and multiple genetic alterations. In some rare cases, such as Timothy syndrome (TS), a specific mutation...
5.
Faizi M, Bader P, Tun C, Encarnacion A, Kleschevnikov A, Belichenko P, et al.
Neurobiol Dis
. 2011 Apr;
43(2):397-413.
PMID: 21527343
Down syndrome (DS) is the most prevalent form of mental retardation caused by genetic abnormalities in humans. This has been successfully modeled in mice to generate the Ts65Dn mouse, a...