Patrick K Albers
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Explore the profile of Patrick K Albers including associated specialties, affiliations and a list of published articles.
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9
Citations
801
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Recent Articles
1.
Suryamohan K, Diwanji D, Stawiski E, Gupta R, Miersch S, Liu J, et al.
Commun Biol
. 2021 Apr;
4(1):475.
PMID: 33846513
COVID-19 is a respiratory illness caused by a novel coronavirus called SARS-CoV-2. The viral spike (S) protein engages the human angiotensin-converting enzyme 2 (ACE2) receptor to invade host cells with...
2.
Vuckovic D, Bao E, Akbari P, Lareau C, Mousas A, Jiang T, et al.
Cell
. 2020 Sep;
182(5):1214-1231.e11.
PMID: 32888494
Blood cells play essential roles in human health, underpinning physiological processes such as immunity, oxygen transport, and clotting, which when perturbed cause a significant global health burden. Here we integrate...
3.
Albers P, McVean G
PLoS Biol
. 2020 Jan;
18(1):e3000586.
PMID: 31951611
The origin and fate of new mutations within species is the fundamental process underlying evolution. However, while much attention has been focused on characterizing the presence, frequency, and phenotypic impact...
4.
Cortes A, Albers P, Dendrou C, Fugger L, McVean G
Nat Genet
. 2019 Dec;
52(1):126-134.
PMID: 31873298
Genetic risk factors frequently affect multiple common human diseases, providing insight into shared pathophysiological pathways and opportunities for therapeutic development. However, systematic identification of genetic profiles of disease risk is...
5.
Kelleher J, Wong Y, Wohns A, Fadil C, Albers P, McVean G
Nat Genet
. 2019 Oct;
51(11):1660.
PMID: 31591513
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
6.
Kelleher J, Wong Y, Wohns A, Fadil C, Albers P, McVean G
Nat Genet
. 2019 Sep;
51(9):1330-1338.
PMID: 31477934
Inferring the full genealogical history of a set of DNA sequences is a core problem in evolutionary biology, because this history encodes information about the events and forces that have...
7.
Valli A, Morotti M, Zois C, Albers P, Soga T, Feldinger K, et al.
Mol Cancer Res
. 2019 Mar;
17(7):1531-1544.
PMID: 30885992
Hypoxia-inducible factor 1α is a key regulator of the hypoxia response in normal and cancer tissues. It is well recognized to regulate glycolysis and is a target for therapy. However,...
8.
Moutsianas L, Agarwala V, Fuchsberger C, Flannick J, Rivas M, Gaulton K, et al.
PLoS Genet
. 2015 Apr;
11(4):e1005165.
PMID: 25906071
Genome and exome sequencing in large cohorts enables characterization of the role of rare variation in complex diseases. Success in this endeavor, however, requires investigators to test a diverse array...
9.
do Amaral F, Albers P, Edwards S, Miyaki C
Mol Ecol
. 2013 Jun;
22(15):3996-4013.
PMID: 23786305
The Atlantic Forest (AF) harbours one of the most diverse vertebrate faunas of the world, including 199 endemic species of birds. Understanding the evolutionary processes behind such diversity has become...