Patrick F Sullivan
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Explore the profile of Patrick F Sullivan including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Ormond C, Ryan N, Hedman A, Cannon T, Sullivan P, Gill M, et al.
Transl Psychiatry
. 2024 Jul;
14(1):313.
PMID: 39080272
Monozygotic (MZ) twins are often thought to have identical genomes, but recent work has shown that early post-zygotic events can result in a spectrum of DNA variants that are different...
12.
Sullivan P, Yao S, Hjerling-Leffler J
Nat Rev Neurosci
. 2024 Jul;
25(9):611-624.
PMID: 39030273
Determining the causes of schizophrenia has been a notoriously intractable problem, resistant to a multitude of investigative approaches over centuries. In recent decades, genomic studies have delivered hundreds of robust...
13.
Puga M, Serrano J, Garcia E, Gonzalez Carracedo M, Jimenez-Canino R, Pino-Yanes M, et al.
J Pers Med
. 2024 Jun;
14(6).
PMID: 38929847
El Hierro is the smallest and westernmost island of the Canary Islands, whose population derives from an admixture of different ancestral components and that has been subjected to genetic isolation....
14.
Bergstedt J, Pasman J, Ma Z, Harder A, Yao S, Parker N, et al.
Nat Cardiovasc Res
. 2024 Jun;
3(6):754-769.
PMID: 38898929
Major depressive disorder (MDD) and cardiovascular disease (CVD) are often comorbid, resulting in excess morbidity and mortality. Here we show that CVDs share most of their genetic risk factors with...
15.
Yang X, Sullivan P, Li B, Fan Z, Ding D, Shu J, et al.
medRxiv
. 2024 Jun;
PMID: 38883759
The UK Biobank (UKB) imaging project is a crucial resource for biomedical research, but is limited to 100,000 participants due to cost and accessibility barriers. Here we used genetic data...
16.
Wong R, Berner L, Sullivan P, Potter C, Dial R
Glob Chang Biol
. 2024 Jun;
30(6):e17374.
PMID: 38863181
In this Technical Advance, we describe a novel method to improve ecological interpretation of remotely sensed vegetation greenness measurements that involved sampling 24,395 Landsat pixels (30 m) across 639 km...
17.
Jonsson L, Horbeck E, Primerano A, Song J, Karlsson R, Smedler E, et al.
Am J Psychiatry
. 2024 Jun;
181(7):620-629.
PMID: 38859703
Objective: Many but not all persons with bipolar disorder require hospital care because of severe mood episodes. Likewise, some but not all patients experience long-term occupational dysfunction that extends beyond...
18.
Pasman J, Bergstedt J, Harder A, Gong T, Xiong Y, Hagg S, et al.
medRxiv
. 2024 Jun;
PMID: 38826420
Background: Major depressive disorder (MDD) is a prevalent and debilitating disorder that has been associated with a range of risk factors and outcomes. Causal pathways between MDD and other traits...
19.
Holla B, Mahadevan J, Ganesh S, Sud R, Janardhanan M, Balachander S, et al.
medRxiv
. 2024 May;
PMID: 38712191
Genome-wide association studies across diverse populations may help validate and confirm genetic contributions to risk of disease. We estimated the extent of population stratification as well as the predictive accuracy...
20.
Mu W, Luo T, Barrera A, Bounds L, Klann T, Ter Weele M, et al.
bioRxiv
. 2024 Apr;
PMID: 38659894
CRISPR epigenomic editing technologies enable functional interrogation of non-coding elements. However, current computational methods for guide RNA (gRNA) design do not effectively predict the power potential, molecular and cellular impact...