Patrick du Souich
Overview
Explore the profile of Patrick du Souich including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
708
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Recent Articles
1.
Vitaloni M, Bemden A, Sciortino R, Carne X, Quintero M, Santos-Moreno P, et al.
BMC Musculoskelet Disord
. 2020 Nov;
21(1):727.
PMID: 33160349
Background: Globally, osteoarthritis (OA) is the third condition associated with disability. There is still poor treatment in OA but science holds the key to finding better treatments and a cure....
2.
Vitaloni M, Bemden A, Sciortino Contreras R, Scotton D, Bibas M, Quintero M, et al.
BMC Musculoskelet Disord
. 2019 Oct;
20(1):493.
PMID: 31656197
Background: Knee osteoarthritis (KOA) is a prevalent form of chronic joint disease associated with functional restrictions and pain. Activity limitations negatively impact social connectedness and psychological well-being, reducing the quality...
3.
Chan G, Hajjar R, Boutin L, Garneau P, Pichette V, Lafrance J, et al.
Am J Transplant
. 2019 Sep;
20(2):582-588.
PMID: 31529773
Laparoscopic sleeve gastrectomy induces weight loss via the creation of a restrictive gastric tube for early satiety and is associated with an accelerated gastric transit time. A prospective, single-dose pharmacokinetic...
4.
Minogianis E, Shams W, Mabrouk O, Wong J, Brake W, Kennedy R, et al.
Eur J Neurosci
. 2018 May;
50(3):2054-2064.
PMID: 29757478
The faster drugs of abuse reach the brain, the greater is the risk of addiction. Even small differences in the rate of drug delivery can influence outcome. Infusing cocaine intravenously...
5.
Hagen N, Cantin L, Constant J, Haller T, Blaise G, Ong-Lam M, et al.
Pain Res Manag
. 2017 May;
2017:7212713.
PMID: 28555092
Objective: This study evaluated subcutaneous injections of tetrodotoxin (TTX) for the treatment of moderate to severe, inadequately controlled cancer-related pain. Methods: Eligible patients were randomized to receive TTX (30 g)...
6.
du Souich P, Roederer G, Dufour R
Pharmacol Ther
. 2017 Feb;
175:1-16.
PMID: 28223230
Statins are effective drugs to reduce cardiovascular events secondary to dyslipidemia; however, they cause frequent undesirable side effects. The incidence of statin-induced myotoxicity (SIM) is presented by 7 to 29%...
7.
Hochberg M, Martel-Pelletier J, Monfort J, Moller I, Castillo J, Arden N, et al.
Ann Rheum Dis
. 2015 Jan;
75(1):37-44.
PMID: 25589511
Objectives: To compare the efficacy and safety of chondroitin sulfate plus glucosamine hydrochloride (CS+GH) versus celecoxib in patients with knee osteoarthritis and severe pain. Methods: Double-blind Multicentre Osteoarthritis interVEntion trial...
8.
du Souich P
Pharmacol Ther
. 2014 Jan;
142(3):362-74.
PMID: 24457028
Symptomatic Slow Acting Drugs for Osteoarthritis (SYSADOA), such as hyaluronic acid (HA), chondroitin sulfate (CS) and glucosamine (GlcN) are natural compounds, composed of repeating disaccharides, used to treat patients with...
9.
Dumais G, Iovu M, du Souich P
Expert Rev Clin Pharmacol
. 2014 Jan;
1(5):627-47.
PMID: 24422735
Inflammatory reactions (IRs), both infectious and aseptic, downregulate numerous enzymes of cytochrome P450 (CYP) and ATP-binding cassette transporters. The mechanism involves proinflammatory cytokines and activation of transcription factors, nuclear factor-κB,...
10.
Iovu M, Heroux L, Verges J, Montell E, Paiement J, du Souich P
Carbohydr Res
. 2012 May;
355:63-8.
PMID: 22633136
This study aimed to assess whether chronic administration of chondroitin sulfate (CS) affects baseline expression of cytochrome P450 isoforms and impedes the decrease in expression and activity of CYP1A2 and...