Patrick C Thiaville
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Explore the profile of Patrick C Thiaville including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
523
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Recent Articles
1.
Bacusmo J, Orsini S, Hu J, deMott M, Thiaville P, Elfarash A, et al.
RNA Biol
. 2017 Jul;
15(4-5):508-517.
PMID: 28726545
Endoribonuclease toxins (ribotoxins) are produced by bacteria and fungi to respond to stress, eliminate non-self competitor species, or interdict virus infection. PrrC is a bacterial ribotoxin that targets and cleaves...
2.
Thiaville J, Kellner S, Yuan Y, Hutinet G, Thiaville P, Jumpathong W, et al.
Proc Natl Acad Sci U S A
. 2016 Mar;
113(11):E1452-9.
PMID: 26929322
The discovery of ∼20-kb gene clusters containing a family of paralogs of tRNA guanosine transglycosylase genes, called tgtA5, alongside 7-cyano-7-deazaguanine (preQ0) synthesis and DNA metabolism genes, led to the hypothesis...
3.
Thiaville P, Legendre R, Rojas-Benitez D, Baudin-Baillieu A, Hatin I, Chalancon G, et al.
Microb Cell
. 2016 Jan;
3(1):29-45.
PMID: 26798630
The universal tRNA modification tA is found at position 37 of nearly all tRNAs decoding ANN codons. The absence of tA leads to severe growth defects in baker's yeast, phenotypes...
4.
Thiaville P, El Yacoubi B, Kohrer C, Thiaville J, Deutsch C, Iwata-Reuyl D, et al.
Mol Microbiol
. 2015 Sep;
98(6):1199-221.
PMID: 26337258
Threonylcarbamoyladenosine (t(6)A) is a modified nucleoside universally conserved in tRNAs in all three kingdoms of life. The recently discovered genes for t(6)A synthesis, including tsaC and tsaD, are essential in...
5.
Rojas-Benitez D, Thiaville P, de Crecy-Lagard V, Glavic A
J Biol Chem
. 2015 Jun;
290(30):18699-707.
PMID: 26063805
N(6)-Threonylcarbamoyl-adenosine (t(6)A) is a universal modification occurring at position 37 in nearly all tRNAs that decode A-starting codons, including the eukaryotic initiator tRNA (tRNAi (Met)). Yeast lacking central components of...
6.
Thiaville P, de Crecy-Lagard V
Microb Cell
. 2015 Mar;
2(1):1-4.
PMID: 25821779
No abstract available.
7.
Thiaville P, Iwata-Reuyl D, de Crecy-Lagard V
RNA Biol
. 2015 Jan;
11(12):1529-39.
PMID: 25629598
The tRNA modification field has a rich literature covering biochemical analysis going back more than 40 years, but many of the corresponding genes were only identified in the last decade....
8.
Kimura S, Miyauchi K, Ikeuchi Y, Thiaville P, de Crecy-Lagard V, Suzuki T
Nucleic Acids Res
. 2014 Jul;
42(14):9350-65.
PMID: 25063302
Methylation is a versatile reaction involved in the synthesis and modification of biologically active molecules, including RNAs. N(6)-methyl-threonylcarbamoyl adenosine (m(6)t(6)A) is a post-transcriptional modification found at position 37 of tRNAs...
9.
Thiaville P, El Yacoubi B, Perrochia L, Hecker A, Prigent M, Thiaville J, et al.
Eukaryot Cell
. 2014 Jul;
13(9):1222-31.
PMID: 25038083
Threonylcarbamoyladenosine (t(6)A) is a universal modification located in the anticodon stem-loop of tRNAs. In yeast, both cytoplasmic and mitochondrial tRNAs are modified. The cytoplasmic t(6)A synthesis pathway was elucidated and...
10.
Naor A, Thiaville P, Altman-Price N, Cohen-Or I, Allers T, de Crecy-Lagard V, et al.
PLoS One
. 2012 Aug;
7(8):e43013.
PMID: 22927945
KEOPS is an important cellular complex conserved in Eukarya, with some subunits conserved in Archaea and Bacteria. This complex was recently found to play an essential role in formation of...