Patricia Szot
Overview
Explore the profile of Patricia Szot including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
20
Citations
506
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Wheeler J, McMillan P, Strovas T, Liachko N, Amlie-Wolf A, Kow R, et al.
Sci Transl Med
. 2019 Dec;
11(523).
PMID: 31852801
Brain lesions composed of pathological tau help to drive neurodegeneration in Alzheimer's disease (AD) and related tauopathies. Here, we identified the mammalian suppressor of tauopathy 2 () gene as a...
2.
Wang L, Raskind M, Wilkinson C, Shofer J, Sikkema C, Szot P, et al.
Int J Geriatr Psychiatry
. 2018 Feb;
33(5):763-768.
PMID: 29446123
Objective: This study evaluated the effects of Alzheimer disease (AD) on the relationship between the brain noradrenergic system and hypothalamic pituitary adrenocortical axis (HPA). Specifically, relationships between cerebrospinal fluid (CSF)...
3.
Szot P, Franklin A, Figlewicz D, Beuca T, Bullock K, Hansen K, et al.
Neuroscience
. 2017 May;
355:9-21.
PMID: 28456715
Neuroinflammation is proposed to be an important component in the development of several central nervous system (CNS) disorders including depression, Alzheimer's disease, Parkinson's disease, and traumatic brain injury. However, exactly...
4.
Cubells J, Schroeder J, Barrie E, Manvich D, Sadee W, Berg T, et al.
PLoS One
. 2016 May;
11(5):e0154864.
PMID: 27148966
Dopamine β-hydroxylase (DBH) converts dopamine (DA) to norepinephrine (NE) in noradrenergic/adrenergic cells. DBH deficiency prevents NE production and causes sympathetic failure, hypotension and ptosis in humans and mice; DBH knockout...
5.
Szot P, Franklin A, Miguelez C, Wang Y, Vidaurrazaga I, Ugedo L, et al.
Neuropharmacology
. 2015 Sep;
101:76-86.
PMID: 26362360
Depression is a common co-morbid condition most often observed in subjects with mild cognitive impairment (MCI) and during the early stages of Alzheimer's disease (AD). Dysfunction of the central noradrenergic...
6.
Szot P, Franklin A, Sikkema C, Wilkinson C, Raskind M
Front Pharmacol
. 2012 Nov;
3:184.
PMID: 23129999
Noradrenergic neurons in the locus coeruleus (LC) are significantly reduced in Parkinson's disease (PD) and the LC exhibits neuropathological changes early in the disease process. It has been suggested that...
7.
Szot P
Epilepsia
. 2012 May;
53 Suppl 1:61-6.
PMID: 22612810
The neurodegenerative disorders Alzheimer's disease (AD) and Parkinson's disease (PD) share in common the neuropathologic loss of locus coeruleus (LC) noradrenergic neurons. In addition, these two neurodegenerative disorders share two...
8.
Falowski S, Sharan A, Reyes B, Sikkema C, Szot P, Van Bockstaele E
Neurosurgery
. 2011 May;
69(6):1281-90.
PMID: 21566538
Background: Recent interest has demonstrated the nucleus accumbens (NAcc) as a potential target for the treatment of depression with deep brain stimulation (DBS). Objective: To demonstrate that DBS of the...
9.
Olson V, Rockett H, Reh R, Redila V, Tran P, Venkov H, et al.
Biol Psychiatry
. 2011 Jan;
70(5):441-8.
PMID: 21251647
Background: Posttraumatic stress disorder (PTSD) is a prevalent psychiatric disorder precipitated by exposure to extreme traumatic stress. Yet, most individuals exposed to traumatic stress do not develop PTSD and may...
10.
McMillan P, White S, Franklin A, Greenup J, Leverenz J, Raskind M, et al.
Brain Res
. 2010 Dec;
1373:240-52.
PMID: 21147074
In Parkinson's disease (PD), there is a significant loss of noradrenergic neurons in the locus coeruleus (LC) in addition to the loss of dopaminergic neurons in the substantia nigra (SN)....