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Patricia Gomez-Molina

Explore the profile of Patricia Gomez-Molina including associated specialties, affiliations and a list of published articles. Areas
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Citations 125
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Recent Articles
1.
Guasp P, Alvarez-Navarro C, Gomez-Molina P, Martin-Esteban A, Marcilla M, Barnea E, et al.
Arthritis Rheumatol . 2015 Sep; 68(2):505-15. PMID: 26360328
Objective: To characterize the peptidome of the Behçet's disease-associated HLA-B*51:01 allotype as well as the differential features of major peptide subsets and their distinct endoplasmic reticulum aminopeptidase 1 (ERAP-1)-mediated processing....
2.
Garcia-Medel N, Sanz-Bravo A, Alvarez-Navarro C, Gomez-Molina P, Barnea E, Marcilla M, et al.
Mol Cell Proteomics . 2014 Sep; 13(12):3367-80. PMID: 25187574
HLA-B27 is strongly associated with ankylosing spondylitis (AS). We analyzed the relationship between structure, peptide specificity, folding, and stability of the seven major HLA-B27 subtypes to determine the role of...
3.
Martin-Esteban A, Gomez-Molina P, Sanz-Bravo A, Lopez de Castro J
J Biol Chem . 2013 Dec; 289(7):3978-90. PMID: 24352655
ERAP1 polymorphism involving residues 528 and 575/725 is associated with ankylosing spondylitis among HLA-B27-positive individuals. We used four recombinant variants to address the combined effects of the K528R and D575N...
4.
Garcia-Medel N, Sanz-Bravo A, Nguyen D, Galocha B, Gomez-Molina P, Martin-Esteban A, et al.
Mol Cell Proteomics . 2012 Aug; 11(11):1416-29. PMID: 22918227
The association of ERAP1 with ankylosing spondylitis (AS)1 among HLA-B27-positive individuals suggests that ERAP1 polymorphism may affect pathogenesis by altering peptide-dependent features of the HLA-B27 molecule. Comparisons of HLA-B*27:04-bound peptidomes...