Patricia A Gonzales
Overview
Explore the profile of Patricia A Gonzales including associated specialties, affiliations and a list of published articles.
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7
Citations
708
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Recent Articles
1.
Schenk L, Bolger S, Luginbuhl K, Gonzales P, Rinschen M, Yu M, et al.
J Am Soc Nephrol
. 2012 Mar;
23(6):1008-18.
PMID: 22440904
Vasopressin controls transport in the renal collecting duct, in part, by regulating transcription. This complex process, which can involve translocation and/or modification of transcriptional regulators, is not completely understood. Here,...
2.
Gonzales P, Zhou H, Pisitkun T, Wang N, Star R, Knepper M, et al.
Methods Mol Biol
. 2010 Apr;
641:89-99.
PMID: 20407943
Exosomes represent an important and readily isolated subset of the urinary proteome that has the potential to shed much insight on the health status of the kidney. Each segment of...
3.
Fernandez-Llama P, Khositseth S, Gonzales P, Star R, Pisitkun T, Knepper M
Kidney Int
. 2010 Feb;
77(8):736-42.
PMID: 20130532
Urinary exosomes have been proposed as starting material for discovery of protein biomarkers of kidney disease. Current protocols for their isolation use a two-step differential centrifugation process. Due to their...
4.
Gonzales P, Pisitkun T, Hoffert J, Tchapyjnikov D, Star R, Kleta R, et al.
J Am Soc Nephrol
. 2008 Dec;
20(2):363-79.
PMID: 19056867
Normal human urine contains large numbers of exosomes, which are 40- to 100-nm vesicles that originate as the internal vesicles in multivesicular bodies from every renal epithelial cell type facing...
5.
Yu M, Pisitkun T, Wang G, Aranda J, Gonzales P, Tchapyjnikov D, et al.
Am J Physiol Cell Physiol
. 2008 Jul;
295(3):C661-78.
PMID: 18596208
In the renal collecting duct, vasopressin controls transport of water and solutes via regulation of membrane transporters such as aquaporin-2 (AQP2) and the epithelial urea transporter UT-A. To discover proteins...
6.
Berdiev B, Cormet-Boyaka E, Tousson A, Qadri Y, Oosterveld-Hut H, Hong J, et al.
J Biol Chem
. 2007 Oct;
282(50):36481-8.
PMID: 17913705
We present the evidence for a direct physical association of cystic fibrosis transmembrane conductance regulator (CFTR) and epithelial sodium channel (ENaC), two major ion channels implicated in the pathophysiology of...
7.
Hoorn E, Pisitkun T, Zietse R, Gross P, Frokiaer J, Wang N, et al.
Nephrology (Carlton)
. 2005 Jun;
10(3):283-90.
PMID: 15958043
Recent progress in biotechnology offers the promise of better medical care at lower costs. Among the techniques that show the greatest promise is mass spectrometry of proteins, which can identify...