Pascale Lesage
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Explore the profile of Pascale Lesage including associated specialties, affiliations and a list of published articles.
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Citations
514
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Recent Articles
21.
Curcio M, Lutz S, Lesage P
Microbiol Spectr
. 2015 Jun;
3(2):MDNA3-0053-2014.
PMID: 26104690
Long-terminal repeat (LTR)-retrotransposons generate a copy of their DNA (cDNA) by reverse transcription of their RNA genome in cytoplasmic nucleocapsids. They are widespread in the eukaryotic kingdom and are the...
22.
Bridier-Nahmias A, Tchalikian-Cosson A, Baller J, Menouni R, Fayol H, Flores A, et al.
Science
. 2015 May;
348(6234):585-8.
PMID: 25931562
Mobile genetic elements are ubiquitous. Their integration site influences genome stability and gene expression. The Ty1 retrotransposon of the yeast Saccharomyces cerevisiae integrates upstream of RNA polymerase III (Pol III)-transcribed...
23.
Curcio M, Lutz S, Lesage P
Microbiol Spectr
. 2015 Apr;
3(2):1-35.
PMID: 25893143
Long-terminal repeat (LTR)-retrotransposons generate a copy of their DNA (cDNA) by reverse transcription of their RNA genome in cytoplasmic nucleocapsids. They are widespread in the eukaryotic kingdom and are the...
24.
Bridier-Nahmias A, Lesage P
Mob DNA
. 2012 Dec;
3(1):22.
PMID: 23244340
Unlabelled: Background: Over the years, a number of reports have revealed that Ty1 integration occurs in a 1-kb window upstream of Pol III-transcribed genes with an approximate 80-bp periodicity between...
25.
Ainouche A, Betermier M, Chandler M, Cordaux R, Cristofari G, Deragon J, et al.
Mob DNA
. 2012 Nov;
3(1):17.
PMID: 23110759
An international conference on Transposable Elements (TEs) was held 21-24 April 2012 in Saint Malo, France. Organized by the French Transposition Community (GDR Elements Génétiques Mobiles et Génomes, CNRS) and...
26.
Servant G, Pinson B, Tchalikian-Cosson A, Coulpier F, Lemoine S, Pennetier C, et al.
Nucleic Acids Res
. 2012 Mar;
40(12):5271-82.
PMID: 22379133
Transposable elements play a fundamental role in genome evolution. It is proposed that their mobility, activated under stress, induces mutations that could confer advantages to the host organism. Transcription of...
27.
Servant G, Pennetier C, Lesage P
Mol Cell Biol
. 2008 Jul;
28(17):5543-54.
PMID: 18591253
The Ty1 long terminal repeat (LTR) retrotransposon of Saccharomyces cerevisiae is a powerful model to understand the activation of transposable elements by stress and their impact on genome expression. We...
28.
Todeschini A, Morillon A, Springer M, Lesage P
Mol Cell Biol
. 2005 Aug;
25(17):7459-72.
PMID: 16107695
Ty1 retrotransposons of the yeast Saccharomyces cerevisiae are activated by different kinds of stress. Here we show that Ty1 transcription is stimulated under severe adenine starvation conditions. The Bas1 transcriptional...
29.
Sacerdot C, Mercier G, Todeschini A, Dutreix M, Springer M, Lesage P
Yeast
. 2005 Apr;
22(6):441-55.
PMID: 15849797
Ty1 elements, LTR-retrotransposons of Saccharomyces cerevisiae, are known to be activated by genetic and environmental stress. Several DNA-damaging agents have been shown to increase both Ty1 transcription and retrotransposition. To...
30.
Morillon A, Benard L, Springer M, Lesage P
Mol Cell Biol
. 2002 Mar;
22(7):2078-88.
PMID: 11884596
Approximately 30 copies of the Ty1 retrotransposon are present in the genome of Saccharomyces cerevisiae. Previous studies gave insights into the global regulation of Ty1 transcription but provided no information...