Paola N Perrat
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Explore the profile of Paola N Perrat including associated specialties, affiliations and a list of published articles.
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9
Citations
507
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Recent Articles
1.
Cebul E, Marivin A, Wexler L, Perrat P, Benard C, Garcia-Marcos M, et al.
bioRxiv
. 2024 Jan;
PMID: 38260503
Adherens junctions (AJs) are a fundamental organizing structure for multicellular life. Although AJs are studied mainly in epithelia, their core function - stabilizing cell contacts by coupling adhesion molecules to...
2.
Blanchette C, Thackeray A, Perrat P, Hekimi S, Benard C
PLoS Genet
. 2017 Jan;
13(1):e1006525.
PMID: 28068429
The regulation of cell migration is essential to animal development and physiology. Heparan sulfate proteoglycans shape the interactions of morphogens and guidance cues with their respective receptors to elicit appropriate...
3.
Barnstedt O, Owald D, Felsenberg J, Brain R, Moszynski J, Talbot C, et al.
Neuron
. 2016 Mar;
89(6):1237-1247.
PMID: 26948892
Memories are stored in the fan-out fan-in neural architectures of the mammalian cerebellum and hippocampus and the insect mushroom bodies. However, whereas key plasticity occurs at glutamatergic synapses in mammals,...
4.
Blanchette C, Perrat P, Thackeray A, Benard C
PLoS Biol
. 2015 Jul;
13(7):e1002183.
PMID: 26148345
Netrin is a key axon guidance cue that orients axon growth during neural circuit formation. However, the mechanisms regulating netrin and its receptors in the extracellular milieu are largely unknown....
5.
Perrat P, Dasgupta S, Wang J, Theurkauf W, Weng Z, Rosbash M, et al.
Science
. 2013 Apr;
340(6128):91-5.
PMID: 23559253
Recent studies in mammals have documented the neural expression and mobility of retrotransposons and have suggested that neural genomes are diverse mosaics. We found that transposition occurs among memory-relevant neurons...
6.
Pitman J, Dasgupta S, Krashes M, Leung B, Perrat P, Waddell S
Fly (Austin)
. 2009 Jan;
3(1):3-9.
PMID: 19164943
A biological understanding of memory remains one of the great quests of neuroscience. For over 30 years the fruit fly Drosophila melanogaster has primarily been viewed as an excellent vehicle...
7.
Kuo Y, Landrette S, Heilman S, Perrat P, Garrett L, Liu P, et al.
Cancer Cell
. 2006 Jan;
9(1):57-68.
PMID: 16413472
The acute myeloid leukemia (AML)-associated CBF beta-SMMHC fusion protein impairs hematopoietic differentiation and predisposes to leukemic transformation. The mechanism of leukemia progression, however, is poorly understood. In this study, we...
8.
Landrette S, Kuo Y, Hensen K, Barjesteh van Waalwijk van Doorn-Khosrovani S, Perrat P, Van de Ven W, et al.
Blood
. 2004 Dec;
105(7):2900-7.
PMID: 15585652
Recurrent chromosomal rearrangements are associated with the development of acute myeloid leukemia (AML). The frequent inversion of chromosome 16 creates the CBFB-MYH11 fusion gene that encodes the fusion protein CBFbeta-SMMHC....
9.
Keene A, Stratmann M, Keller A, Perrat P, Vosshall L, Waddell S
Neuron
. 2004 Oct;
44(3):521-33.
PMID: 15504331
Amnesiac mutant flies have an olfactory memory defect. The amn gene encodes a homolog of vertebrate pituitary adenylate cyclase-activating peptide (PACAP), and it is strongly expressed in dorsal paired medial...