Scott Waddell
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Explore the profile of Scott Waddell including associated specialties, affiliations and a list of published articles.
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83
Citations
4684
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Recent Articles
1.
Okray Z, Jacob P, Moszynski J, Talbot C, Waddell S
Cold Spring Harb Protoc
. 2024 Oct;
PMID: 39389622
Olfactory classical conditioning paradigms have been extensively used since the early 1970s to apply genetic approaches to the study of memory in Over the intervening years, advances in genetics have...
2.
Okray Z, Waddell S
Cold Spring Harb Protoc
. 2024 Oct;
PMID: 39389621
Memory has been extensively studied in since the early 1970s. Straightforward aversive and appetitive conditioning paradigms train populations of flies to associate the pairing of one of two odors with...
3.
Compensatory enhancement of input maintains aversive dopaminergic reinforcement in hungry Drosophila
Meschi E, Duquenoy L, Otto N, Dempsey G, Waddell S
Neuron
. 2024 May;
112(14):2315-2332.e8.
PMID: 38795709
Hungry animals need compensatory mechanisms to maintain flexible brain function, while modulation reconfigures circuits to prioritize resource seeking. In Drosophila, hunger inhibits aversively reinforcing dopaminergic neurons (DANs) to permit the...
4.
Jovanoski K, Duquenoy L, Mitchell J, Kapoor I, Treiber C, Croset V, et al.
Nature
. 2023 Nov;
624(7991):E5.
PMID: 38012376
No abstract available.
5.
Jovanoski K, Duquenoy L, Mitchell J, Kapoor I, Treiber C, Croset V, et al.
Nature
. 2023 Oct;
623(7986):356-365.
PMID: 37880370
Resource-seeking behaviours are ordinarily constrained by physiological needs and threats of danger, and the loss of these controls is associated with pathological reward seeking. Although dysfunction of the dopaminergic valuation...
6.
Buck S, Rubin S, Kunkhyen T, Treiber C, Xue X, Fenno L, et al.
bioRxiv
. 2023 Oct;
PMID: 37873436
Parkinson's disease (PD) targets some dopamine (DA) neurons more than others. Sex differences offer insights, with females more protected from DA neurodegeneration. The mammalian vesicular glutamate transporter VGLUT2 and ortholog...
7.
Okray Z, Jacob P, Stern C, Desmond K, Otto N, Talbot C, et al.
Nature
. 2023 Apr;
617(7962):777-784.
PMID: 37100911
Associating multiple sensory cues with objects and experience is a fundamental brain process that improves object recognition and memory performance. However, neural mechanisms that bind sensory features during learning and...
8.
Villar M, Pavao-Delgado M, Amigo M, Jacob P, Merabet N, Pinot A, et al.
Curr Biol
. 2022 Sep;
32(21):4576-4592.e5.
PMID: 36103878
Animals use prior experience to assign absolute (good or bad) and relative (better or worse) value to new experience. These learned values guide appropriate later decision making. Even though our...
9.
10.
Park A, Croset V, Otto N, Agarwal D, Treiber C, Meschi E, et al.
Curr Biol
. 2022 Aug;
32(18):3952-3970.e8.
PMID: 35963239
Thirst emerges from a range of cellular changes that ultimately motivate an animal to consume water. Although thirst-responsive neuronal signals have been reported, the full complement of brain responses is...