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Panagiotis Tsiakanikas

Explore the profile of Panagiotis Tsiakanikas including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 192
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Recent Articles
1.
Adamopoulos P, Bartzoka N, Tsiakanikas P, Scorilas A
Gene . 2024 Nov; 936:149092. PMID: 39549777
The human angiotensin converting enzyme 2 (ACE2) gene encodes a type I transmembrane protein, which is homologous to angiotensin I-converting enzyme (ACE) and belongs to the angiotensin-converting enzyme family of...
2.
Daneva G, Tsiakanikas P, Adamopoulos P, Scorilas A
Expert Opin Ther Targets . 2024 Oct; 28(10):875-894. PMID: 39431595
Introduction: Human kallikrein-related peptidases (KLKs) represent a subgroup of 15 serine endopeptidases involved in various physiological processes and pathologies, including cancer. Areas Covered: This review aims to provide a comprehensive...
3.
Tsiakanikas P, Athanasopoulou K, Darioti I, Agiassoti V, Theocharis S, Scorilas A, et al.
Life (Basel) . 2024 Aug; 14(8). PMID: 39202666
Extrachromosomal circular DNA (eccDNA) is a form of a circular double-stranded DNA that exists independently of conventional chromosomes. eccDNA exhibits a broad and random distribution across eukaryotic cells and has...
4.
Diamantopoulos M, Adamopoulos P, Tsiakanikas P, Nisotakis T, Skourou P, Scorilas A
Gene . 2024 Aug; 930:148856. PMID: 39147115
The human NTHL1 gene encodes a DNA glycosylase that plays a key role in the base excision repair (BER) pathway, repairing oxidative DNA damage and maintaining genome integrity. The physiological...
5.
Adamopoulos P, Athanasopoulou K, Boti M, Dimitroulis G, Daneva G, Tsiakanikas P, et al.
RNA Biol . 2023 Jun; 20(1):281-295. PMID: 37272060
Breast Cancer Gene 1 (BRCA1) is a tumour suppressor protein that modulates multiple biological processes including genomic stability and DNA damage repair. Although the main BRCA1 protein is well characterized,...
6.
Papadimitriou M, Soureas K, Papanota A, Tsiakanikas P, Adamopoulos P, Ntanasis-Stathopoulos I, et al.
J Transl Med . 2023 Apr; 21(1):245. PMID: 37024879
Background: Despite significant advancements in multiple myeloma (MM) therapy, the highly heterogenous treatment response hinders reliable prognosis and tailored therapeutics. Herein, we have studied the clinical utility of miRNAs in...
7.
Tsiakanikas P, Adamopoulos P, Tsirba D, Artemaki P, Papadopoulos I, Kontos C, et al.
Biomedicines . 2022 May; 10(5). PMID: 35625858
Colorectal cancer (CRC) is the second most lethal cause of cancer-related deaths in Europe. Fragments of tRNA are conserved among vertebrates, characterized by pleiotropic regulatory functions and have been found...
8.
Adamopoulos P, Tsiakanikas P, Stolidi I, Scorilas A
BMC Genomics . 2022 Feb; 23(1):163. PMID: 35219290
Background: Technological advancements in the era of massive parallel sequencing have enabled the functional dissection of the human transcriptome. However, 5' ends of mRNAs are significantly underrepresented in these datasets,...
9.
Adamopoulos P, Tsiakanikas P, Boti M, Scorilas A
Int J Mol Sci . 2021 Dec; 22(24). PMID: 34948093
The complicity of human RAS proteins in cancer is a well-documented fact, both due to the mutational hyperactivation of these GTPases and the overexpression of the genes encoding these proteins....
10.
Adamopoulos P, Athanasopoulou K, Tsiakanikas P, Scorilas A
FEBS J . 2021 Sep; 289(3):712-729. PMID: 34535948
Cyclin-dependent kinase 4 (CDK4) is a member of the cyclin-dependent kinases, a family of protein kinases with outstanding roles in signaling pathways, transcription regulation, and cell division. Defective or overactivated...