P Y Lum
Overview
Explore the profile of P Y Lum including associated specialties, affiliations and a list of published articles.
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19
Citations
1463
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0
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Recent Articles
1.
Epel E, Puterman E, Lin J, Blackburn E, Lum P, Beckmann N, et al.
Transl Psychiatry
. 2016 Aug;
6(8):e880.
PMID: 27576169
Meditation is becoming increasingly practiced, especially for stress-related medical conditions. Meditation may improve cellular health; however, studies have not separated out effects of meditation from vacation-like effects in a residential...
2.
Lum P, Singh G, Lehman A, Ishkanov T, Vejdemo-Johansson M, Alagappan M, et al.
Sci Rep
. 2013 Feb;
3:1236.
PMID: 23393618
This paper applies topological methods to study complex high dimensional data sets by extracting shapes (patterns) and obtaining insights about them. Our method combines the best features of existing standard...
3.
Zhu J, Lum P, Lamb J, GuhaThakurta D, Edwards S, Thieringer R, et al.
Cytogenet Genome Res
. 2004 Jul;
105(2-4):363-74.
PMID: 15237224
The reconstruction of genetic networks in mammalian systems is one of the primary goals in biological research, especially as such reconstructions relate to elucidating not only common, polygenic human diseases,...
4.
Chang C, Swaan P, Ngo L, Lum P, Patil S, Unadkat J
Mol Pharmacol
. 2004 Feb;
65(3):558-70.
PMID: 14978234
Concentrative nucleoside transporters (CNTs) and equilibrative nucleoside transporters (ENTs) are important in physiological and pharmacological activity and disposition of nucleosides and nucleoside drugs. A better understanding of the structural requirements...
5.
Waring J, Jolly R, Ciurlionis R, Lum P, Praestgaard J, Morfitt D, et al.
Toxicol Appl Pharmacol
. 2001 Aug;
175(1):28-42.
PMID: 11509024
Microarray technology, which allows one to quantitate the expression of thousands of genes simultaneously, has begun to have a major impact on many different areas of drug discovery and development....
6.
Shoemaker D, Schadt E, Armour C, He Y, McDonagh P, Loerch P, et al.
Nature
. 2001 Mar;
409(6822):922-7.
PMID: 11237012
The most important product of the sequencing of a genome is a complete, accurate catalogue of genes and their products, primarily messenger RNA transcripts and their cognate proteins. Such a...
7.
Lum P, Ngo L, BAKKEN A, Unadkat J
Cancer Chemother Pharmacol
. 2001 Feb;
45(4):273-8.
PMID: 10755314
Purpose: To clone and sequence the equilibrative nitrobenzylthioinosine (NBMPR)-sensitive nucleoside transporter (es) from the human small intestine and to examine the capacities of nucleosides and nucleoside analogs to inhibit the...
8.
Hughes T, Marton M, Jones A, Roberts C, STOUGHTON R, Armour C, et al.
Cell
. 2000 Aug;
102(1):109-26.
PMID: 10929718
Ascertaining the impact of uncharacterized perturbations on the cell is a fundamental problem in biology. Here, we describe how a single assay can be used to monitor hundreds of different...
9.
Lum P, Edwards S, Wright R
Yeast
. 1996 Sep;
12(11):1107-24.
PMID: 8896278
The synthesis of mevalonate, a molecule required for both sterol and isoprene biosynthesis in eukaryotes, is catalysed by 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase. Using a gene dosage approach, we have...
10.
Lum P, Wright R
J Cell Biol
. 1995 Oct;
131(1):81-94.
PMID: 7559789
Elevated levels of certain membrane proteins, including the sterol biosynthetic enzyme HMG-CoA reductase, induce proliferation of the endoplasmic reticulum. When the amounts of these proteins return to basal levels, the...