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P S Rabinovitch

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Articles 143
Citations 3472
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Recent Articles
1.
Dai D, Chiao Y, Martin G, Marcinek D, Basisty N, Quarles E, et al.
Prog Mol Biol Transl Sci . 2017 Mar; 146:203-241. PMID: 28253986
The free-radical theory of aging was proposed more than 50 years ago. As one of the most popular mechanisms explaining the aging process, it has been extensively studied in several...
2.
Potter A, Grossmann A, Rabinovitch P, Eaton D, Kavanagh T
Toxicol In Vitro . 2010 Jul; 11(4):355-63. PMID: 20654322
An increase in cytosolic free calcium ([Ca(2+)](i)) is one of the earliest events to occur in T lymphocytes following stimulation of the transmembrane T cell receptor/CD3 complex (TCR/CD3). This [Ca(2+)](i)...
3.
Dunn J, Mackenzie G, Oukrif D, Mosse C, Banks M, Thorpe S, et al.
Br J Cancer . 2010 May; 102(11):1608-17. PMID: 20461081
Background And Aims: DNA ploidy abnormalities (aneuploidy/tetraploidy) measured by flow cytometry (FC) are strong predictors of future cancer development in untreated Barrett's oesophagus, independent of histology grade. Image cytometric DNA...
4.
June C, Abe R, Rabinovitch P
Curr Protoc Cytom . 2008 Sep; Chapter 9:Unit 9.8. PMID: 18770760
Using flow cytometry, single-cell measurements of calcium can be made on isolated populations identified by one or more phenotypic characteristics. This unit describes the preparation of cells, including labeling with...
5.
Poot M, Rosato M, Rabinovitch P
Curr Protoc Cytom . 2008 Sep; Chapter 7:Unit 7.14. PMID: 18770726
Halogenated deoxyuridines such as BrdU incorporated into DNA in place of thymidine can be detected by virtue of their ability to quench the fluorescence of Hoechst dyes. This property is...
6.
Ogburn C, Austad S, Holmes D, Kiklevich J, Gollahon K, Rabinovitch P, et al.
J Gerontol A Biol Sci Med Sci . 2008 Mar; 53(4):B287-92. PMID: 18314559
Current mechanistic theories of aging would predict that many species of birds, given their unusually high metabolic rates, body temperatures, and blood sugar levels, should age more rapidly than mammals...
7.
Barrett M, Glogovac J, Prevo L, Reid B, Porter P, Rabinovitch P
Biotechniques . 2002 Apr; 32(4):888-90, 892, 894, 896. PMID: 11962610
Microarray technologies have made possible comprehensive analyses of nucleic acid sequence and expression. However, the technology to obtain efficiently high-quality RNA and DNA suitable for array analysis from purified populations...
8.
Rabinovitch P, Longton G, Blount P, Levine D, Reid B
Am J Gastroenterol . 2001 Nov; 96(11):3071-83. PMID: 11721752
Objectives: Barrett's esophagus develops in 5-10% of patients with gastroesophageal reflux disease and predisposes to esophageal adenocarcinoma. We have previously shown that a systematic baseline endoscopic biopsy protocol using flow...
9.
Reid B, Prevo L, Galipeau P, Sanchez C, Longton G, Levine D, et al.
Am J Gastroenterol . 2001 Nov; 96(10):2839-48. PMID: 11693316
Objectives: Most patients with Barrett's esophagus do not progress to cancer, but those who do seem to have markedly increased survival when cancers are detected at an early stage. Most...
10.
Rosato M, Jabbour A, Ponce R, Kavanagh T, Takaro T, Hill J, et al.
J Immunol Methods . 2001 Aug; 256(1-2):35-46. PMID: 11516753
One method for examining cell cycle kinetics by flow cytometry uses continuous DNA labeling with bromodeoxyuridine (BrdU), a thymidine analogue. Upon incorporation into DNA, BrdU causes stoichiometric quenching of the...