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M Kubbies

Explore the profile of M Kubbies including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 51
Citations 288
Followers 0
Related Specialties
Cell Biology
Allergy & Immunology
Molecular Biology
Top 10 Co-Authors
P S Rabinovitch
H Hoehn
D Schindler
A W Machl
G Giese
B Goller
M Poot
P Traub
S A Planitzer
T Bettecken
Published In
Cytometry
Exp Cell Res
J Cell Physiol
Hum Genet
Cell Prolif
Affiliations
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Recent Articles
1.
Exposure to continuous bromodeoxyuridine (BrdU) differentially affects cell cycle progression of human breast and bladder cancer cell lines
Diermeier S, Schmidt-Bruecken E, Kubbies M, Kunz-Schughart L, Brockhoff G
Cell Prolif . 2004 Mar; 37(2):195-206. PMID: 15030553
Incorporation of bromodeoxyuridine (BrdU) during DNA replication is frequently used for cell cycle analysis. The flow cytometric BrdU/Hoechst quenching technique is conducive to high-resolution assessment of cell cycle kinetics, but...
2.
Expression and function of tight junction associated molecules in human breast tumor cells is not affected by the Ras-MEK1 pathway
Macek R, Swisshelm K, Kubbies M
Cell Mol Biol (Noisy-le-grand) . 2003 Jul; 49(1):1-11. PMID: 12839332
Constitutive activation of Ras or Ras-mediated signaling pathways is one of the initial steps during tumorigenesis that promotes neoplastic transformation. Recently it was reported that in Ha-Ras overexpressing MDCK cells...
3.
Nonradioactive labeling and detection of mRNAs hybridized onto nucleic acid cDNA arrays
Hoevel T, Kubbies M
Methods Mol Biol . 2002 Jan; 185:417-23. PMID: 11769005
No abstract available.
4.
Genomic organization of claudin-1 and its assessment in hereditary and sporadic breast cancer
Kramer F, White K, Kubbies M, Swisshelm K, Weber B
Hum Genet . 2000 Nov; 107(3):249-56. PMID: 11071387
Human claudin-1 is an integral protein component of tight junctions, a structure controlling cell-to-cell adhesion and, consequently, regulating paracellular and transcellular transport of solutes across human epithelia and endothelia. Recently,...
5.
Cisplatin-digoxigenin mRNA labeling for nonradioactive detection of mRNA hybridized onto nucleic acid cDNA arrays
Hoevel T, Holz H, Kubbies M
Biotechniques . 1999 Nov; 27(5):1064-7. PMID: 10572654
We optimized a novel nonradioactive hybridization technique using a cis-platin coupled digoxigenin derivative for direct labeling of mRNA. This new mRNA reporter molecule was applied to cDNA membrane arrays to...
6.
SEMP1, a senescence-associated cDNA isolated from human mammary epithelial cells, is a member of an epithelial membrane protein superfamily
Swisshelm K, Machl A, Planitzer S, Robertson R, Kubbies M, Hosier S
Gene . 1999 Feb; 226(2):285-95. PMID: 9931503
We have cloned a human cDNA, SEMP1 (senescence-associated epithelial membrane protein 1), using differential display (DD) of mRNA. We compared mRNA expression profiles between cultured normal senescent human mammary epithelial...
7.
Small deletions in the regulatory 3' UTR of the human alpha-tropomyosin gene identified by differential display
Planitzer S, Machl A, Schindler D, Kubbies M
Mol Cell Probes . 1998 Jun; 12(1):35-40. PMID: 9584076
The differential display technique (DDT) was used to compare Fanconi anaemia (FA) fibroblasts with those of normal controls in a screen for genes involved in DNA repair, recognizing and handling...
8.
Identification of a novel c-DNA overexpressed in Fanconi's anemia fibroblasts partially homologous to a putative L-3-phosphoserine-phosphatase
Planitzer S, Machl A, Rueckels M, Kubbies M
Gene . 1998 May; 210(2):297-306. PMID: 9573387
We applied the cDNA differential display technique (DDT) in a DNA-repair deficient cell model to isolate genes involved in dysregulation of cell proliferation and development of cancer. The comparative analysis...
9.
Applicability of nonsyngeneic cell models for screening of genes in monogenetic diseases via differential display technique
Planitzer S, Machl A, Kubbies M
Electrophoresis . 1998 Mar; 18(15):2865-70. PMID: 9504823
Conventional subtraction library techniques or DNA-transfection studies are standard techniques applied for identification and isolation of genes relevant in monogenetic diseases like Fanconi anemia (FA). The differential display technique (DDT)...
10.
1-NGFR receptor is a new flow cytometric tool for rapid cell cycle-correlated gene therapy complementation studies in viable cells
Machl A, Planitzer S, Kubbies M
Cytometry . 1998 Jan; 29(4):371-4. PMID: 9415420
Control of successful genetic complementation of cellular defects in heterogenous cell populations requires biochemical selection markers or cell analytical specifiers. With available gene therapy technologies, only a fraction of a...