P S Grabowski
Overview
Explore the profile of P S Grabowski including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
486
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Recent Articles
1.
Holmes S, Still K, Buttle D, Bishop N, Grabowski P
Bone
. 2004 Jul;
35(2):471-8.
PMID: 15268899
Chemically modified tetracyclines (CMTs) are thought to inhibit bone resorption primarily through their ability to inhibit matrix metalloproteinases (MMPs). We have previously demonstrated that some tetracycline compounds (TCs) induce apoptosis...
2.
Helfrich M, Hobson R, Grabowski P, Zurbriggen A, Cosby S, Dickson G, et al.
J Bone Miner Res
. 2000 Dec;
15(12):2315-29.
PMID: 11127197
Paget's disease of bone is a common bone disease characterized by increased and disorganized bone remodeling at focal sites throughout the skeleton. The etiology of the disease is unresolved. A...
3.
Bettany J, Peet N, Wolowacz R, Skerry T, Grabowski P
Bone
. 2000 Jun;
27(1):75-80.
PMID: 10865212
Chemically modified tetracyclines (CMTs) are thought to inhibit bone resorption through inhibition of matrix metalloproteinases. Here we report that some tetracyclines also induce apoptosis in rabbit osteoclasts and inhibit differentiation...
4.
Ward M, Grabowski P, Ellis A, Secombes C
Immunology
. 2000 Jan;
99(1):153-61.
PMID: 10651954
Following injection challenge of rainbow trout with the Gram-positive pathogen Renibacterium salmoninarum, serum nitrate levels increased indicative of NO production. The timing and amount of nitrate produced varied with the...
5.
Armour K, vant Hof R, Grabowski P, Reid D, Ralston S
J Bone Miner Res
. 2000 Jan;
14(12):2137-42.
PMID: 10620073
Inflammatory disease is associated with increased production of nitric oxide (NO) and activation of the inducible nitric oxide synthase (iNOS) pathway. Several studies have addressed the role of NO as...
6.
Peet N, Grabowski P, Skerry T
FASEB J
. 1999 Dec;
13(15):2179-85.
PMID: 10593865
Recent identification in bone of transporters, receptors, and components of synaptic signaling suggests a role for glutamate in the skeleton. We investigated effects of glutamate and its antagonist MK801 on...
7.
Zou J, Grabowski P, Cunningham C, Secombes C
Cytokine
. 1999 Aug;
11(8):552-60.
PMID: 10433801
The complete coding sequence of rainbow trout IL-1beta has been obtained. The gene contains a short 5' UTR (97 bp), a 780 bp open reading frame and a 466 bp...
8.
Laing K, Hardie L, Aartsen W, Grabowski P, Secombes C
Dev Comp Immunol
. 1999 Apr;
23(1):71-85.
PMID: 10220070
Using oligonucleotide primers based on mammalian nitric oxide synthases (NOS), expression of an inducible NOS (iNOS) gene was detected in head kidney and gill tissue of bacterially-challenged rainbow trout. Three...
9.
Hardie L, Laing K, Daniels G, Grabowski P, Cunningham C, Secombes C
Cytokine
. 1998 Sep;
10(8):555-63.
PMID: 9722928
The nucleotide sequence of a rainbow trout transforming growth factor beta (TGF-beta) peptide is presented, which translates into a 382 amino acid precursor molecule containing a 20 amino acid leader...
10.
Hoey S, Grabowski P, Ralston S, Forrester J, Liversidge J
J Immunol
. 1997 Nov;
159(10):5132-42.
PMID: 9366443
The production of large amounts of nitric oxide (NO) by inducible nitric oxide synthase (iNOS) has been described as a double-edged sword eliciting pro- or anti-inflammatory effects in different immune...