P R Murdock
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Explore the profile of P R Murdock including associated specialties, affiliations and a list of published articles.
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18
Citations
508
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Recent Articles
1.
Moore D, Chambers J, Murdock P, Emson P
Neuropharmacology
. 2002 Nov;
43(6):966-78.
PMID: 12423666
We report here that human Ntera-2/D1 (NT-2) cells, an undifferentiated committed neuronal progenitor cell line, endogenously express a functional P2Y(1) receptor, while other P2Y subtypes, except perhaps P2Y(4), are not...
2.
Connor J, Kumar S, Sathe G, Mooney J, OBrien S, Mui P, et al.
Osteoarthritis Cartilage
. 2002 Feb;
9(8):727-37.
PMID: 11795992
Objective: To characterize the expression pattern of clusterin in adult human normal and osteoarthritic cartilage. Methods: Clusterin mRNA expression in adult human normal and osteoarthritic cartilage was investigated by analysis...
3.
Moore D, Chambers J, Wahlin J, Tan K, Moore G, Jenkins O, et al.
Biochim Biophys Acta
. 2001 Nov;
1521(1-3):107-19.
PMID: 11690642
The diverse biological actions of extracellular nucleotides in tissues and cells are mediated by two distinct classes of P2 receptor, P2X and P2Y. The G protein-coupled P2Y receptors comprise at...
4.
Jowsey I, Thomson A, Flanagan J, Murdock P, Moore G, Meyer D, et al.
Biochem J
. 2001 Oct;
359(Pt 3):507-16.
PMID: 11672424
GSH-dependent prostaglandin D(2) synthase (PGDS) enzymes represent the only vertebrate members of class Sigma glutathione S-transferases (GSTs) identified to date. Complementary DNA clones encoding the orthologous human and rat GSH-dependent...
5.
Karagiannis S, Warrack J, Jennings K, Murdock P, Christie G, Moulder K, et al.
Immunology
. 2001 Jul;
103(3):319-31.
PMID: 11454061
The presentation of extremely low doses of antigen to T cells is enhanced by immunoglobulin E (IgE)-dependent antigen focusing to CD23, the low-affinity receptor for IgE, expressed on activated B...
6.
Meadows H, Chapman C, Duckworth D, Kelsell R, Murdock P, Nasir S, et al.
Brain Res
. 2001 Feb;
892(1):94-101.
PMID: 11172753
We have cloned and functionally expressed the human orthologue of the mouse TRAAK gene. When cDNA for hTRAAK is expressed in either Xenopus oocytes or HEK293 cells it forms a...
7.
Hussain I, Powell D, Howlett D, Chapman G, Gilmour L, Murdock P, et al.
Mol Cell Neurosci
. 2000 Nov;
16(5):609-19.
PMID: 11083922
Sequential proteolytic processing of the Amyloid Precursor Protein (APP) by beta- and gamma-secretases generates the 4-kDa amyloid (A beta) peptide, a key component of the amyloid plaques seen in Alzheimer's...
8.
Chapman C, Meadows H, Godden R, Campbell D, Duckworth M, Kelsell R, et al.
Brain Res Mol Brain Res
. 2000 Oct;
82(1-2):74-83.
PMID: 11042359
We have isolated, by degenerate PCR, a complementary DNA encoding a novel two pore domain potassium channel. This is the 7th functional member of the human tandem pore domain potassium...
9.
FITZGERALD L, Dytko G, Sarau H, Mannan I, Ellis C, Lane P, et al.
Biochem Biophys Res Commun
. 2000 Jul;
273(3):805-10.
PMID: 10891327
We have identified a cDNA, designated HOFNH30, which encodes a 354 amino acid G-protein-coupled receptor (GPCR). This receptor has 96% amino acid identity to the Jurkat-T cell-derived EDG7 and could...
10.
Kikly K, Bochner B, Freeman S, Tan K, Gallagher K, Dalessio K, et al.
J Allergy Clin Immunol
. 2000 Jun;
105(6 Pt 1):1093-100.
PMID: 10856141
Background: Eosinophils, basophils, and mast cells are believed to be the central tenet cells in allergic conditions including allergic rhinitis, asthma, and eczema. The molecular mechanisms underlying the recruitment of...