P N Pharr
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Explore the profile of P N Pharr including associated specialties, affiliations and a list of published articles.
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14
Citations
220
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Recent Articles
1.
Watowich S, Mikami A, Busche R, Xie X, Pharr P, Longmore G
J Interferon Cytokine Res
. 2001 Jan;
20(12):1065-70.
PMID: 11152572
Erythropoietin (Epo) is essential for formation of mature red blood cells (RBC). However, the function of Epo receptor (EpoR)-dependent signaling pathways in the regulation of erythropoiesis remains unclear. To determine...
2.
Pharr P, Hofbauer A, Worthington R, Longmore G
Int J Hematol
. 2000 Oct;
72(2):178-85.
PMID: 11039666
Erythropoiesis is severely impaired in mice with inactivating mutations in the Steel factor (SF) gene (Sl/Sl mice) or in c-kit, in the SF receptor gene (W/W mice), and in mice...
3.
Spyropoulos D, Pharr P, Lavenburg K, Jackers P, Papas T, Ogawa M, et al.
Mol Cell Biol
. 2000 Jul;
20(15):5643-52.
PMID: 10891501
The Ets family of transcription factors have been suggested to function as key regulators of hematopoeisis. Here we describe aberrant hematopoeisis and hemorrhaging in mouse embryos homozygous for a targeted...
4.
Pharr P, Hofbauer A
Exp Hematol
. 1997 Jul;
25(7):620-8.
PMID: 9216738
The expression of c-kit and flk-2/flt3 was analyzed in various stages of mast cell differentiation using reverse transcriptase polymerase chain reaction (RT-PCR). Mouse fetal liver cells were sorted using antibodies...
5.
Pharr P, Ogawa M, Hofbauer A, Longmore G
Proc Natl Acad Sci U S A
. 1994 Aug;
91(16):7482-6.
PMID: 8052607
Whether the presence of specific receptors on the surface of developing cells is the cause or consequence of lineage restriction is not known. If activation of specific receptors is the...
6.
Williams D, Zimmers T, PIERCE J, Pharr P, Schechter A, Sawyer S, et al.
Ann N Y Acad Sci
. 1994 Apr;
718:232-43; discussion 243-4.
PMID: 7514379
No abstract available.
7.
Longmore G, Pharr P, Lodish H
Mol Cell Biol
. 1994 Apr;
14(4):2266-77.
PMID: 8139532
If the env gene of spleen focus-forming virus (SFFV) is replaced by a cDNA encoding a constitutively active form of the erythropoietin receptor, EPO-R(R129C), the resultant recombinant virus, SFFVcEPO-R, induces...
8.
Pharr P, HANKINS D, Hofbauer A, Lodish H, Longmore G
Proc Natl Acad Sci U S A
. 1993 Feb;
90(3):938-42.
PMID: 7679218
We tested the ability of a constitutively activated erythropoietin receptor [EpoR(R129C)] to alter the growth requirements of primary hematopoietic precursors that terminally differentiate in culture. Two recombinant retroviruses expressing EpoR(R129C),...
9.
Pharr P, Ogawa M
Leukemia
. 1990 Mar;
4(3):210-5.
PMID: 2156115
We recently developed a new progenitor assay using murine fetal liver cells that provides a source of pluripotent progenitors, bipotent progenitors, and committed macrophage, megakaryocyte, erythroid, and mast cell progenitors....
10.
Pharr P, Ogawa M
Exp Hematol
. 1988 Oct;
16(9):748-51.
PMID: 3262529
Isolated progenitors of defined type are useful for definitive studies of commitment, growth factor specificity, and identification of viral target cells. Blast cell colonies from cultures of spleen cells obtained...