P Moullier
Overview
Explore the profile of P Moullier including associated specialties, affiliations and a list of published articles.
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Articles
52
Citations
792
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Recent Articles
1.
Ameline B, Tshilenge K, Weber M, Biget M, Libeau L, Caplette R, et al.
Gene Ther
. 2017 Sep;
24(11):735-741.
PMID: 28880021
Several preclinical studies have investigated the potential of algal channelrhodopsin and human melanopsin as optogenetic tools for vision restoration. In the present study, we assessed the potentially deleterious effects of...
2.
Neuberger E, Perez I, Le Guiner C, Moser D, Ehlert T, Allais M, et al.
Gene Ther
. 2016 Jan;
23(4):330-9.
PMID: 26752352
For ethical and safety reasons it is critical to develop easily implemented assays with high sensitivity and specificity for gene doping surveillance. Two nested quantitative real-time PCR (qPCR) assays were...
3.
Hordeaux J, Dubreil L, Deniaud J, Iacobelli F, Moreau S, Ledevin M, et al.
Gene Ther
. 2015 Jan;
22(4):316-24.
PMID: 25588740
Intracerebral administration of recombinant adeno-associated vector (AAV) has been performed in several clinical trials. However, delivery into the brain requires multiple injections and is not efficient to target the spinal...
4.
Bucher T, Dubreil L, Colle M, Maquigneau M, Deniaud J, Ledevin M, et al.
Gene Ther
. 2014 Feb;
21(5):522-8.
PMID: 24572783
Systemic and intracerebrospinal fluid delivery of adeno-associated virus serotype 9 (AAV9) has been shown to achieve widespread gene delivery to the central nervous system (CNS). However, after systemic injection, the...
5.
Naffakh N, Moullier P, Salvetti A, Bohl D, Danos O, Heard J
Restor Neurol Neurosci
. 2011 May;
8(1):67-9.
PMID: 21551810
No abstract available.
6.
Ni W, Le Guiner C, Gernoux G, Penaud-Budloo M, Moullier P, Snyder R
Gene Ther
. 2011 Mar;
18(7):709-18.
PMID: 21390073
Legitimate uses of gene transfer technology can benefit from sensitive detection methods to determine vector biodistribution in pre-clinical studies and in human clinical trials, and similar methods can detect illegitimate...
7.
Moreau A, Hill M, Thebault P, Deschamps J, Chiffoleau E, Chauveau C, et al.
FASEB J
. 2009 May;
23(9):3070-7.
PMID: 19420134
Clinical translation of dendritic cell (DC)-based cell therapy requires preclinical studies in nonhuman primates (NHPs). The aim of this work was to establish the in vitro conditions for generation of...
8.
Stieger K, Mendes-Madeira A, Meur G, Weber M, Deschamps J, Nivard D, et al.
Gene Ther
. 2007 Oct;
14(23):1668-73.
PMID: 17914405
Gene transfer of neurotrophic or antiangiogenic factors has been shown to improve photoreceptor survival in retinal degenerative disorders (that is retinitis pigmentosa) and to prevent neovascularization in retinal vascular diseases...
9.
Le Meur G, Stieger K, Smith A, Weber M, Deschamps J, Nivard D, et al.
Gene Ther
. 2006 Oct;
14(4):292-303.
PMID: 17024105
Previous studies have tested gene replacement therapy in RPE65-deficient dogs using recombinant adeno-associated virus 2/2 (rAAV2/2), -2/1 or -2/5 mediated delivery of the RPE65 gene. They all documented restoration of...
10.
Fraefel C, Mendes-Madeira A, Mabon O, Lefebvre A, Le Meur G, Ackermann M, et al.
Gene Ther
. 2005 May;
12(16):1283-8.
PMID: 15889134
The purpose of our study was to evaluate the transduction profiles of herpes simplex virus type 1 (HSV-1)-based amplicon vectors following subretinal injection in the rat. Two amplicon vectors were...