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P Moullier

Explore the profile of P Moullier including associated specialties, affiliations and a list of published articles. Areas
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Articles 52
Citations 792
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Recent Articles
11.
Verdugo M, Scarpino V, Moullier P, Haskins M, Aguirre G, Ray J
Curr Eye Res . 2002 Mar; 23(5):357-67. PMID: 11910525
Purpose: To develop an effective therapy for treating glycosaminoglycan (GAG) storage in mucopolysaccharidosis VII (MPS VII) retinal pigment epithelium (RPE) in vitro using adenoviral vector mediated human beta-glucuronidase cDNA (Ad-GUSB)...
12.
Negre D, Duisit G, Mangeot P, Moullier P, Darlix J, Cosset F
Curr Top Microbiol Immunol . 2002 Mar; 261:53-74. PMID: 11892253
No abstract available.
13.
Favre D, Provost N, Blouin V, Blancho G, Cherel Y, Salvetti A, et al.
Mol Ther . 2001 Dec; 4(6):559-66. PMID: 11735340
Previous studies on distribution and toxicity of viral vectors administered in monkeys indicated that the nonhuman primate model has a reasonable predictive value for clinical applications. In this study, eight...
14.
Nony P, Tessier J, Chadeuf G, Ward P, Giraud A, Dugast M, et al.
J Virol . 2001 Sep; 75(20):9991-4. PMID: 11559833
This study identifies a region of the adeno-associated virus type 2 (AAV-2) rep gene (nucleotides 190 to 540 of wild-type AAV-2) as a cis-acting Rep-dependent element able to promote the...
15.
Serguera C, Sarkis C, Ridet J, Colin P, Moullier P, Mallet J
Mol Ther . 2001 Jun; 3(6):875-81. PMID: 11407901
Astrocytes are a good candidate cell type for brain transplantation: They are endogenous to the CNS, they have efficient secretory machinery, and they play a major role in neuronal support....
16.
Agard C, Ligeza C, Dupas B, Izembart A, El Kouri C, Moullier P, et al.
Cancer Gene Ther . 2001 Mar; 8(2):128-36. PMID: 11263528
Gene transfer of the herpes simplex virus thymidine kinase (HSV-tk) gene sensitizes tumor cells to the toxic effect of ganciclovir (GCV). The toxic effect of GCV extends to nontransduced surrounding...
17.
Tessier J, Chadeuf G, Nony P, Avet-Loiseau H, Moullier P, Salvetti A
J Virol . 2000 Dec; 75(1):375-83. PMID: 11119606
Stable packaging cell lines expressing the rep and cap genes for recombinant adeno-associated virus type 2 (rAAV-2) assembly constitute an attractive alternative to transient transfection protocols. We recently characterized a...
18.
Negre D, Mangeot P, Duisit G, Blanchard S, Vidalain P, Leissner P, et al.
Gene Ther . 2000 Nov; 7(19):1613-23. PMID: 11083469
We describe the generation and the characterization of new lentiviral vectors derived from SIVmac251, a simian immunodeficiency virus (SIV). A methodical approach was used to engineer both efficient and safe...
19.
Favre D, Ferry N, Moullier P
J Am Soc Nephrol . 2000 Nov; 11 Suppl 16:S149-53. PMID: 11065348
Viral vectors have been used in vitro and in vivo for more than a decade, with some significant results in specific situations, e.g., when recombinant adeno-associated virus is used for...
20.
Favre D, Cherel Y, Provost N, Blouin V, Ferry N, Moullier P, et al.
Gene Ther . 2000 Sep; 7(16):1417-20. PMID: 10981669
Skeletal muscle is a privileged target for long-term rAAV-mediated gene transfer in mouse, rat, dog and non-human primates. Intramuscular injections of rAAV encoding human factor IX in hemophilia B patients...