P Lorenzo Bozzelli
Overview
Explore the profile of P Lorenzo Bozzelli including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
16
Citations
356
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Rodrigues-Amorim D, Bozzelli P, Kim T, Liu L, Gibson O, Yang C, et al.
Nat Commun
. 2024 Aug;
15(1):6744.
PMID: 39112447
Demyelination is a common pathological feature in a wide range of diseases, characterized by the loss of myelin sheath and myelin-supporting oligodendrocytes. These losses lead to impaired axonal function, increased...
2.
3.
Welch G, Boix C, Schmauch E, Davila-Velderrain J, Victor M, Dileep V, et al.
Sci Adv
. 2022 Sep;
8(39):eabo4662.
PMID: 36170369
DNA double-strand breaks (DSBs) are linked to neurodegeneration and senescence. However, it is not clear how DSB-bearing neurons influence neuroinflammation associated with neurodegeneration. Here, we characterize DSB-bearing neurons from the...
4.
Adaikkan C, Wang J, Abdelaal K, Middleton S, Bozzelli P, Wickersham I, et al.
Neuron
. 2022 Aug;
110(19):3091-3105.e9.
PMID: 35987206
A major pathological hallmark of neurodegenerative diseases, including Alzheimer's, is a significant reduction in the white matter connecting the two cerebral hemispheres, as well as in the correlated activity between...
5.
Victor M, Leary N, Luna X, Meharena H, Scannail A, Bozzelli P, et al.
Cell Stem Cell
. 2022 Aug;
29(8):1197-1212.e8.
PMID: 35931030
Apolipoprotein E4 (APOE4) is the greatest known genetic risk factor for developing sporadic Alzheimer's disease. How the interaction of APOE4 microglia with neurons differs from microglia expressing the disease-neutral APOE3...
6.
Barker S, Raju R, Milman N, Wang J, Davila-Velderrain J, Gunter-Rahman F, et al.
Sci Transl Med
. 2021 Nov;
13(618):eabd7695.
PMID: 34731014
Recent increases in human longevity have been accompanied by a rise in the incidence of dementia, highlighting the need to preserve cognitive function in an aging population. A small percentage...
7.
Caccavano A, Bozzelli P, Forcelli P, Pak D, Wu J, Conant K, et al.
J Neurosci
. 2020 May;
40(26):5116-5136.
PMID: 32439703
Memory disruption in mild cognitive impairment (MCI) and Alzheimer's disease (AD) is poorly understood, particularly at early stages preceding neurodegeneration. In mouse models of AD, there are disruptions to sharp...
8.
Bozzelli P, Caccavano A, Avdoshina V, Mocchetti I, Wu J, Conant K
Exp Neurol
. 2019 Nov;
323:113077.
PMID: 31678140
HIV-associated neurocognitive disorders (HAND) continue to persist despite effective control of viral replication. Although the mechanisms underlying HAND are poorly understood, recent attention has focused on altered neuronal population activity...
9.
Bozzelli P, Yin T, Avdoshina V, Mocchetti I, Conant K, Maguire-Zeiss K
Glia
. 2019 May;
67(9):1719-1729.
PMID: 31124192
The HIV-1 protein Tat is continually released by HIV-infected cells despite effective combination antiretroviral therapies (cART). Tat promotes neurotoxicity through enhanced expression of proinflammatory molecules from resident and infiltrating immune...
10.
Sepulveda-Rodriguez A, Li P, Khan T, Ma J, Carlone C, Bozzelli P, et al.
eNeuro
. 2019 May;
6(2).
PMID: 31058213
Microglia are in a privileged position to both affect and be affected by neuroinflammation, neuronal activity and injury, which are all hallmarks of seizures and the epilepsies. Hippocampal microglia become...