P L Jacobs
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Explore the profile of P L Jacobs including associated specialties, affiliations and a list of published articles.
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Articles
20
Citations
246
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Recent Articles
1.
van de Wetering-Krebbers S, Jacobs P, Kemperman G, Spaans E, Peeters P, Delbressine L, et al.
Drug Metab Dispos
. 2010 Dec;
39(4):580-90.
PMID: 21177986
The metabolism and excretion of asenapine [(3aRS,12bRS)-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]-oxepino [4,5-c]pyrrole (2Z)-2-butenedioate (1:1)] were studied after sublingual administration of [(14)C]-asenapine to healthy male volunteers. Mean total excretion on the basis of the percent...
2.
Delbressine L, Moonen M, Kaspersen F, Wagenaars G, Jacobs P, Timmer C, et al.
Clin Drug Investig
. 2008 Mar;
15(1):45-55.
PMID: 18370465
This paper investigated the pharmacokinetics and biotransformation of mirtazapine in healthy human volunteers. The results showed that the area under the plasma drug concentration-time curve (AUC) of mirtazapine in human...
3.
Nash M, Mintz C, Montalvo B, Jacobs P
J Spinal Cord Med
. 2007 Jun;
23(4):221-7.
PMID: 17536290
Objective: The hemodynamic effects of slow sequential compression (SCD) were compared with rapid intermittent pulsatile compression (IPC) in subjects with complete tetraplegia. Methods: Twenty subjects underwent Doppler examination of the...
4.
Nash M, Jacobs P, Mendez A, Goldberg R
J Spinal Cord Med
. 2001 Oct;
24(1):2-9.
PMID: 11587430
Background: People with chronic paraplegia frequently experience dyslipidemias characterized by depressed levels of high-density lipoprotein cholesterol (HDL-C) and elevated levels of low-density lipoprotein cholesterol (LDL-C). These abnormal lipid profiles and...
5.
Jacobs P, Nash M
J Spinal Cord Med
. 2001 Oct;
24(1):10-8.
PMID: 11587428
Background: Sedentary lifestyles and physical deconditioning are commonly reported among persons with spinal cord injury (SCI), although many forms of exercise have been shown to be beneficial. For individuals unable...
6.
Bursi R, De Gooyer M, Grootenhuis A, Jacobs P, Van Der Louw J, Leysen D
J Mol Graph Model
. 2001 Sep;
19(6):552-6, 607-8.
PMID: 11552683
Metabolic stability is a key issue in the development of orally active androgens for Partial Androgen Deficiency in Aging Males (PADAM) and male contraception. Rates of metabolism in human hepatocyte...
7.
Jacobs P, Nash M, Rusinowski J
Med Sci Sports Exerc
. 2001 Apr;
33(5):711-7.
PMID: 11323537
Purpose: This study tested the safety and the effects of circuit resistance training (CRT) on peak upper extremity cardiorespiratory endurance and muscle strength in chronic survivors of paraplegia due to...
8.
Nash M, Spielholz N, Jacobs P
Arch Phys Med Rehabil
. 2000 Jul;
81(7):1000-2.
PMID: 10896021
No abstract available.
9.
Nash M, Jacobs P
Med Sci Sports Exerc
. 1998 Aug;
30(8):1336-8.
PMID: 9710878
No abstract available.
10.
Nash M, Jacobs P, Klerk K, Green B
Arch Phys Med Rehabil
. 1998 Jul;
79(7):873-6.
PMID: 9685107
This single-subject case examined oxyhemoglobin saturation and alveolar end-tidal carbon dioxide levels in a ventilator-dependent tetraplegic patient undergoing electrical stimulation cycle ergometry. When exercising with a closed tracheostomy cuff under...