P L Brubaker
Overview
Explore the profile of P L Brubaker including associated specialties, affiliations and a list of published articles.
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90
Citations
2383
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Recent Articles
1.
Bodie G, Hagen J, Almamar A, Majumdar S, Wang X, Tuepah R, et al.
Can J Surg
. 2022 Apr;
55(4 Suppl 1):S63-S135.
PMID: 35488395
No abstract available.
2.
Martchenko S, Sweeney M, Dimitriadou V, Murray J, Brubaker P
J Pharmacol Exp Ther
. 2020 Mar;
373(3):347-352.
PMID: 32144124
Long-acting glucagon-like peptide-2 receptor (GLP-2R) agonists are well-established to increase intestinal growth in rodents and, most notably, humans with short bowel syndrome. Most of the trophic effects of GLP-2R agonists...
3.
Suppression of circadian secretion of glucagon-like peptide-1 by the saturated fatty acid, palmitate
Martchenko A, Oh R, Wheeler S, Gurges P, Chalmers J, Brubaker P
Acta Physiol (Oxf)
. 2017 Dec;
222(4):e13007.
PMID: 29193800
Aim: Glucagon-like peptide-1 is an incretin hormone secreted by the intestinal L-cell with a circadian rhythm that parallels expression of the core clock gene, Bmal1. Although feeding rats a high-fat/high-sucrose...
4.
Mohajeri S, Perkins B, Brubaker P, Riddell M
Diabet Med
. 2015 May;
32(11):1425-37.
PMID: 25962798
Although regular physical activity is encouraged for individuals with diabetes, exercise at high altitude increases risk for a number of potential complications. This review highlights our current understanding of the...
5.
Poreba M, Dong C, Li S, Stahl A, Miner J, Brubaker P
Am J Physiol Endocrinol Metab
. 2012 Aug;
303(7):E899-907.
PMID: 22871340
The antidiabetic intestinal L cell hormone glucagon-like peptide-1 (GLP-1) enhances glucose-dependent insulin secretion and inhibits gastric emptying. GLP-1 secretion is stimulated by luminal oleic acid (OA), which crosses the cell...
6.
Wong V, Oh A, Chassot A, Chaboissier M, Brubaker P
Diabetologia
. 2011 Apr;
54(7):1726-34.
PMID: 21484214
Aims/hypothesis: Roof plate-specific spondin (R-spondin1; RSPO1) is a modulator of canonical Wg (wingless) plus Int1 (chromosomal integration site of mouse mammary tumour virus on mouse chromosome 15) (cWNT) signalling that...
7.
Jackson Huang T, Brubaker P
Endocrine
. 2010 Dec;
3(7):499-503.
PMID: 21153205
Secretion of the intestinal proglucagon-derived peptides (PGDPs) including the incretin glucagon-like peptide-1 (GLP-1) is regulated, at least in part, by the duodenal hormone glucose-dependent insulinotropic peptide (GIP) through a protein...
8.
Gronau K, Brubaker P
Endocrine
. 2010 Dec;
3(11):795-9.
PMID: 21153123
Glucagon-like peptide-1(7-37/36NH2) (GLP-1) potently stimulates acute glucose-dependent insulin secretionin vitro andin vivo. Islet cell lines have been used extensively to examine the effects of GLP-1(7-37/36NH2) on adenylyl cyclase as well...
9.
Lauffer L, Iakoubov R, Brubaker P
Endocrinology
. 2008 Apr;
149(5):2035-7.
PMID: 18427153
No abstract available.
10.
Wong V, Brubaker P
Minerva Endocrinol
. 2006 May;
31(2):107-24.
PMID: 16682935
Type 2 diabetes mellitus and its clinical correlates, including impaired fasting blood glucose, obesity and insulin resistance, represent a significant public health issue worldwide, with the prevalence of these metabolic...