P J Wirth
Overview
Explore the profile of P J Wirth including associated specialties, affiliations and a list of published articles.
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Articles
74
Citations
361
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Recent Articles
1.
Wirth P, Henderson Berg M, Sadick N
Skin Therapy Lett
. 2017 Nov;
22(6):5-7.
PMID: 29091380
Approximately 16 million Americans have rosacea, an inflammatory cutaneous disorder with central facial erythema, papules, pustules, telangiectasia, flushing, and swelling being among the more commonly recognized features. Overexpression of cathelicidin...
2.
Sun Q, Zappacosta F, Factor V, Wirth P, Hatfield D, Gladyshev V
J Biol Chem
. 2000 Nov;
276(5):3106-14.
PMID: 11060283
Animal thioredoxin reductases (TRs) are selenocysteine-containing flavoenzymes that utilize NADPH for reduction of thioredoxins and other protein and nonprotein substrates. Three types of mammalian TRs are known, with TR1 being...
3.
Conner E, Lemmer E, Omori M, Wirth P, Factor V, Thorgeirsson S
Oncogene
. 2000 Oct;
19(44):5054-62.
PMID: 11042693
Deregulation of E2F transcriptional control has been implicated in oncogenic transformation. Consistent with this idea, we recently demonstrated that during hepatocarcinogenesis in c-myc/TGFalpha double transgenic mice, there is increased expression...
4.
Appella E, Arnott D, Sakaguchi K, Wirth P
EXS
. 2000 May;
88:1-27.
PMID: 10803368
The high resolving power of two-dimensional polyacrylamide gel electrophoresis 2D-PAGE and its full analytical and preparative potential have been described with special emphasis on reproducibility and standardization of protein spot...
5.
Bergman A, Benjamin T, Alaiya A, Waltham M, Sakaguchi K, Franzen B, et al.
Electrophoresis
. 2000 Mar;
21(3):679-86.
PMID: 10726777
Two-dimensional gel electrophoresis with subsequent analysis by mass spectrometry was applied to study differences in protein expression between benign and malignant solid tumors from human beast, lung and ovary cells....
6.
Conner E, Teramoto T, Wirth P, Kiss A, Garfield S, Thorgeirsson S
Carcinogenesis
. 1999 May;
20(4):583-90.
PMID: 10223185
Current studies have indicated both positive and negative roles for the hepatocyte growth factor (HGF)/c-met receptor signaling system in tumor development. Recently, we have shown that HGF has the capacity...
7.
Factor V, Kiss A, Woitach J, Wirth P, Thorgeirsson S
J Biol Chem
. 1998 Jun;
273(25):15846-53.
PMID: 9624185
In previous studies we have demonstrated that transforming growth factor (TGF)-alpha/c-myc double transgenic mice exhibit an enhanced rate of cell proliferation, accumulate extensive DNA damage, and develop multiple liver tumors...
8.
Conner E, Wirth P, Kiss A, Santoni-Rugiu E, Thorgeirsson S
Biochem Biophys Res Commun
. 1997 Jul;
236(2):396-401.
PMID: 9240448
Recently we demonstrated in a transgenic mouse model that hepatocyte growth factor (HGF) inhibits c-myc dependent hepatocarcinogenesis. The inhibitory effects of HGF in carcinogenesis were further characterized using a series...
9.
Woitach J, Conner E, Wirth P, Thorgeirsson S
J Cell Biochem
. 1997 Mar;
64(4):651-60.
PMID: 9093914
In an attempt to elucidate the mechanism by which c-myc and transforming growth factor-alpha (TGF-alpha) cooperate in hepatocyte tumor development, we have analyzed signaling by the epidermal growth factor (EGF)...
10.
Wirth P, Luo L, Hoang T, Benjamin T
Recent Results Cancer Res
. 1997 Jan;
143:145-60.
PMID: 8912417
No abstract available.