P J Mroz
Overview
Explore the profile of P J Mroz including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
12
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0
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Recent Articles
1.
Moolten F, Vonderhaar B, Mroz P
Hum Gene Ther
. 1996 Jun;
7(10):1197-204.
PMID: 8793544
Drug sensitivity ("suicide") genes can sensitize cancer cells to chemotherapy, but therapeutic use of these genes is limited by difficulties in delivering them to all areas of established cancers. An...
2.
Tamiya T, Ono Y, Wei M, Mroz P, Moolten F, Chiocca E
Cancer Gene Ther
. 1996 May;
3(3):155-62.
PMID: 8725879
Genes that encode enzymes that convert inactive "prodrugs" into anticancer metabolites may be therapeutically useful against brain tumors. Unlike other genes tested to date in brain tumor models, the Escherichia...
3.
Mroz P, Moolten F
Hum Gene Ther
. 1993 Oct;
4(5):589-95.
PMID: 8280797
"Suicide genes" encoding exceptional sensitivity to chemotherapeutic agents can potentially improve the selectivity of cancer therapy. As a component of a retroviral gene therapy vector, a suicide gene might also...
4.
Moolten F, Wells J, Mroz P
Cancer Lett
. 1992 Jul;
64(3):257-63.
PMID: 1322236
The potential value of retroviral gene transfer as a means of targeting therapeutic genes to neoplastic cells is threatened by the tendency of occasional cells to lose transduced genes or...