P J Kushner
Overview
Explore the profile of P J Kushner including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
46
Citations
3402
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Fanning S, Hodges-Gallagher L, Myles D, Sun R, Fowler C, Plant I, et al.
Nat Commun
. 2018 Jun;
9(1):2368.
PMID: 29915250
Complex tissue-specific and cell-specific signaling by the estrogen receptor (ER) frequently leads to the development of resistance to endocrine therapy for breast cancer. Pure ER antagonists, which completely lack tissue-specific...
2.
Wang L, Ting M, Kushner P
Sci Rep
. 2017 Mar;
7(1):279.
PMID: 28325893
A key determinant of winter weather and climate in Europe and North America is the North Atlantic Oscillation (NAO), the dominant mode of atmospheric variability in the Atlantic domain. Skilful...
3.
Laliberte F, Zika J, Mudryk L, Kushner P, Kjellsson J, Doos K
Science
. 2015 Jan;
347(6221):540-3.
PMID: 25635098
Incoming and outgoing solar radiation couple with heat exchange at Earth's surface to drive weather patterns that redistribute heat and moisture around the globe, creating an atmospheric heat engine. Here,...
4.
Lopez G, Turck C, Schaufele F, Stallcup M, Kushner P
J Biol Chem
. 2001 Apr;
276(25):22177-82.
PMID: 11301320
Promoter-bound steroid receptors activate gene expression by recruiting members of the p160 family of coactivators. Many steroid receptors, most notably the progesterone and estrogen receptors, are regulated both by cognate...
5.
Wang C, Fu M, Angeletti R, Reutens A, Albanese C, Lisanti M, et al.
J Biol Chem
. 2001 Mar;
276(21):18375-83.
PMID: 11279135
Regulation of nuclear receptor gene expression involves dynamic and coordinated interactions with histone acetyl transferase (HAT) and deacetylase complexes. The estrogen receptor (ERalpha) contains two transactivation domains regulating ligand-independent and...
6.
Fan S, Ma Y, Wang C, Yuan R, Meng Q, Wang J, et al.
Oncogene
. 2001 Mar;
20(1):77-87.
PMID: 11244506
The BRCA1 gene was previously found to inhibit the transcriptional activity of the estrogen receptor [ER-alpha] in human breast and prostate cancer cell lines. In this study, we found that...
7.
Kushner P, Agard D, Greene G, Scanlan T, Shiau A, Uht R, et al.
J Steroid Biochem Mol Biol
. 2001 Feb;
74(5):311-7.
PMID: 11162939
Estrogen receptor (ER) binds to estrogen response elements in target genes and recruits a coactivator complex of CBP-pl60 that mediates stimulation of transcription. ER also activates transcription at AP-1 sites...
8.
Feng W, Webb P, Nguyen P, Liu X, Li J, Karin M, et al.
Mol Endocrinol
. 2001 Jan;
15(1):32-45.
PMID: 11145737
Estrogen receptor (ER) is activated either by ligand or by signals from tyrosine kinase-linked cell surface receptors. We investigated whether the nonreceptor Src tyrosine kinase could affect ER activity. Expression...
9.
Webb P, Anderson C, Valentine C, Nguyen P, Marimuthu A, West B, et al.
Mol Endocrinol
. 2000 Dec;
14(12):1976-85.
PMID: 11117528
Unliganded thyroid hormone receptors (TRs) repress transcription through recruitment of corepressors, including nuclear receptor corepressor (N-CoR). We find that N-CoR contains three interaction domains (IDs) that bind to TR, rather...
10.
Webb P, Nguyen P, Valentine C, Weatherman R, Scanlan T, Kushner P
J Biol Chem
. 2000 Sep;
275(48):37552-8.
PMID: 10986290
Antiestrogens, including tamoxifen and raloxifene, block estrogen receptor (ER) action by blocking the interactions of an estrogen-dependent activation function (AF-2) with p160 coactivators. Although tamoxifen does show some agonist activity...